AIMC Topic: Prostate

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Harnessing clinical annotations to improve deep learning performance in prostate segmentation.

PloS one
PURPOSE: Developing large-scale datasets with research-quality annotations is challenging due to the high cost of refining clinically generated markup into high precision annotations. We evaluated the direct use of a large dataset with only clinicall...

Preclinical evaluation of a markerless, real-time, augmented reality guidance system for robot-assisted radical prostatectomy.

International journal of computer assisted radiology and surgery
PURPOSE: Intra-operative augmented reality (AR) during surgery can mitigate incomplete cancer removal by overlaying the anatomical boundaries extracted from medical imaging data onto the camera image. In this paper, we present the first such complete...

Domain adaptation for segmentation of critical structures for prostate cancer therapy.

Scientific reports
Preoperative assessment of the proximity of critical structures to the tumors is crucial in avoiding unnecessary damage during prostate cancer treatment. A patient-specific 3D anatomical model of those structures, namely the neurovascular bundles (NV...

Discovery of primary prostate cancer biomarkers using cross cancer learning.

Scientific reports
Prostate cancer (PCa), the second leading cause of cancer death in American men, is a relatively slow-growing malignancy with multiple early treatment options. Yet, a significant number of low-risk PCa patients are over-diagnosed and over-treated wit...

Development and head-to-head comparison of machine-learning models to identify patients requiring prostate biopsy.

BMC urology
BACKGROUND: Machine learning has many attractive theoretic properties, specifically, the ability to handle non predefined relations. Additionally, studies have validated the clinical utility of mpMRI for the detection and localization of CSPCa (Gleas...

Male pelvic multi-organ segmentation on transrectal ultrasound using anchor-free mask CNN.

Medical physics
PURPOSE: Current prostate brachytherapy uses transrectal ultrasound images for implant guidance, where contours of the prostate and organs-at-risk are necessary for treatment planning and dose evaluation. This work aims to develop a deep learning-bas...

Combining weakly and strongly supervised learning improves strong supervision in Gleason pattern classification.

BMC medical imaging
BACKGROUND: One challenge to train deep convolutional neural network (CNNs) models with whole slide images (WSIs) is providing the required large number of costly, manually annotated image regions. Strategies to alleviate the scarcity of annotated da...

Digital Frozen Sections with Fluorescence Confocal Microscopy During Robot-assisted Radical Prostatectomy: Surgical Technique.

European urology
BACKGROUND: Robot-assisted radical prostatectomy (RARP) involves a tradeoff between oncological control and functional outcomes. Intraoperative control of surgical margins (SMs) may help in ensuring the safety of the dissection. Fluorescence confocal...

Extraperitoneal versus transperitoneal approach for robot-assisted radical prostatectomy: a contemporary systematic review and meta-analysis.

Journal of robotic surgery
We aim to evaluate the differences in peri-operative characteristics, surgical complications, and oncological and functional control between the extraperitoneal RARP (EP-RARP) and transperitoneal RARP (TP-RARP). A comprehensive database search was pe...