BACKGROUND: Prostate cancer is a common malignancy among elderly males with a growing incidence. While prostate biopsy remains the gold standard for diagnosis, this invasive procedure is poorly tolerated by some patients. The Gleason grade group (GGG...
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Nov 3, 2025
Prostate-specific membrane antigen (PSMA) PET has the potential to monitor the response to taxane-based chemotherapy in patients with prostate cancer and shows promise for predicting outcomes and improving response evaluation. This retrospective stud...
Medical science monitor : international medical journal of experimental and clinical research
Oct 19, 2025
BACKGROUND Accurate spatial correlation between preoperative prostate MRI and post-prostatectomy histopathology is critical for improving prostate cancer diagnosis, treatment planning, and MRI interpretation. Current manual registration methods are t...
The seminal vesicle region plays a crucial role in male reproductive health, and its accurate evaluation is essential for diagnosing infertility and carcinoma. Magnetic resonance imaging (MRI) is the primary modality for assessment; however, manual e...
Prostate cancer is characterized by an immunosuppressive tumour environment. This work combines Raman spectroscopy with group-and-bases-restricted non-negative matrix factorization (GBR-NMF) and machine learning to assemble models of immune cell dens...
Journal of experimental & clinical cancer research : CR
Oct 16, 2025
The high intra-patient heterogeneity in multifocal primary prostate cancer (PCa) has curtailed the efficacy of current treatment options. By employing twin biopsies from multiple lesions with matched patient-derived organoids (PDO) models, the PCa mo...
The aggressiveness of prostate cancer is primarily assessed from histopathological data using the Gleason scoring system. Conventional artificial intelligence (AI) approaches can predict Gleason scores, but often lack explainability, which may limit ...
Proposed methods for prostate cancer screening are currently prohibitively expensive (due to the high costs of imaging equipment such as magnetic resonance imaging and traditional ultrasound systems), inadequate in their detection rates, require high...
Prostate cancer remains a leading cause of mortality, necessitating precise histopathological segmentation for accurate Gleason Grade assessment. However, existing deep learning-based segmentation models lack contextual awareness and explainability, ...
Robotic-assisted radical prostatectomy (RARP) has become the gold standard treatment for localized prostate cancer. However, predicting post-operative outcomes remains challenging. This study aims to develop and validate predictive models for key out...
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