AIMC Topic: Radiotherapy Dosage

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Dose distribution prediction in isodose feature-preserving voxelization domain using deep convolutional neural network.

Medical physics
PURPOSE: To implement a framework for dose prediction using a deep convolutional neural network (CNN) based on the concept of isodose feature-preserving voxelization (IFPV) in simplifying the representation of the dose distribution.

Intelligent inverse treatment planning via deep reinforcement learning, a proof-of-principle study in high dose-rate brachytherapy for cervical cancer.

Physics in medicine and biology
Inverse treatment planning in radiation therapy is formulated as solving optimization problems. The objective function and constraints consist of multiple terms designed for different clinical and practical considerations. Weighting factors of these ...

Predicting VMAT patient-specific QA results using a support vector classifier trained on treatment plan characteristics and linac QC metrics.

Physics in medicine and biology
The use of treatment plan characteristics to predict patient-specific quality assurance (QA) measurement results has recently been reported as a strategy to help facilitate automated pre-treatment verification workflows or to provide a virtual assess...

MRI-only brain radiotherapy: Assessing the dosimetric accuracy of synthetic CT images generated using a deep learning approach.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
PURPOSE: This study assessed the dosimetric accuracy of synthetic CT images generated from magnetic resonance imaging (MRI) data for focal brain radiation therapy, using a deep learning approach.

Stochastic frontier analysis as knowledge-based model to improve sparing of organs-at-risk for VMAT-treated prostate cancer.

Physics in medicine and biology
Stochastic frontier analysis (SFA) is used as a novel knowledge-based technique in order to develop a predictive model of dosimetric features from significant geometric parameters describing a patient morphology. 406 patients treated with VMAT for pr...

Dosimetric study on learning-based cone-beam CT correction in adaptive radiation therapy.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists
INTRODUCTION: Cone-beam CT (CBCT) image quality is important for its quantitative analysis in adaptive radiation therapy. However, due to severe artifacts, the CBCTs are primarily used for verifying patient setup only so far. We have developed a lear...

A deep learning- and partial least square regression-based model observer for a low-contrast lesion detection task in CT.

Medical physics
PURPOSE: This work aims to develop a new framework of image quality assessment using deep learning-based model observer (DL-MO) and to validate it in a low-contrast lesion detection task that involves CT images with patient anatomical background.

3D radiotherapy dose prediction on head and neck cancer patients with a hierarchically densely connected U-net deep learning architecture.

Physics in medicine and biology
The treatment planning process for patients with head and neck (H&N) cancer is regarded as one of the most complicated due to large target volume, multiple prescription dose levels, and many radiation-sensitive critical structures near the target. Tr...