AIMC Topic: Reference Standards

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Leveraging Electronic Dental Record Data to Classify Patients Based on Their Smoking Intensity.

Methods of information in medicine
BACKGROUND: Smoking is an established risk factor for oral diseases and, therefore, dental clinicians routinely assess and record their patients' detailed smoking status. Researchers have successfully extracted smoking history from electronic health ...

Virtual histological staining of unlabelled tissue-autofluorescence images via deep learning.

Nature biomedical engineering
The histological analysis of tissue samples, widely used for disease diagnosis, involves lengthy and laborious tissue preparation. Here, we show that a convolutional neural network trained using a generative adversarial-network model can transform wi...

Streamlining Quality Review of Mass Spectrometry Data in the Clinical Laboratory by Use of Machine Learning.

Archives of pathology & laboratory medicine
CONTEXT.—: Turnaround time and productivity of clinical mass spectrometric (MS) testing are hampered by time-consuming manual review of the analytical quality of MS data before release of patient results.

Qualitative versus quantitative lumbar spinal stenosis grading by machine learning supported texture analysis-Experience from the LSOS study cohort.

European journal of radiology
PURPOSE: To investigate and compare the reproducibility and accuracy of qualitative ratings and quantitative texture analysis (TA) in detection and grading of lumbar spinal stenosis (LSS) in magnetic resonance imaging (MR) scans of the lumbar spine.

The practical implementation of artificial intelligence technologies in medicine.

Nature medicine
The development of artificial intelligence (AI)-based technologies in medicine is advancing rapidly, but real-world clinical implementation has not yet become a reality. Here we review some of the key practical issues surrounding the implementation o...

Development of a sandwich ELISA for determining plasma prolactin concentration in domestic birds.

Domestic animal endocrinology
The present study was conducted to establish a sandwich ELISA for the determination of prolactin (PRL) concentrations in the plasma of domestic fowls. The assay uses a recombinant goose PRL as the reference standard, expressed in a eukaryotic system,...

Detecting Evidence of Intra-abdominal Surgical Site Infections from Radiology Reports Using Natural Language Processing.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Free-text reports in electronic health records (EHRs) contain medically significant information - signs, symptoms, findings, diagnoses - recorded by clinicians during patient encounters. These reports contain rich clinical information which can be le...

Grader Variability and the Importance of Reference Standards for Evaluating Machine Learning Models for Diabetic Retinopathy.

Ophthalmology
PURPOSE: Use adjudication to quantify errors in diabetic retinopathy (DR) grading based on individual graders and majority decision, and to train an improved automated algorithm for DR grading.

Identifying term relations cross different gene ontology categories.

BMC bioinformatics
BACKGROUND: The Gene Ontology (GO) is a community-based bioinformatics resource that employs ontologies to represent biological knowledge and describes information about gene and gene product function. GO includes three independent categories: molecu...