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Risk Assessment

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An efficient artificial neural network-based optimization techniques for the early prediction of coronary heart disease: comprehensive analysis.

Scientific reports
Coronary heart disease (CHD) is the world's leading cause of death, contributing to a high mortality rate. This emphasizes the requirement for an advanced decision support system in order to evaluate the risk of CHD. This study presents an Artificial...

Advancing Alzheimer's disease risk prediction: development and validation of a machine learning-based preclinical screening model in a cross-sectional study.

BMJ open
OBJECTIVES: Alzheimer's disease (AD) poses a significant challenge for individuals aged 65 and older, being the most prevalent form of dementia. Although existing AD risk prediction tools demonstrate high accuracy, their complexity and limited access...

Development and Validation of a Machine Learning Algorithm for Predicting Diabetes Retinopathy in Patients With Type 2 Diabetes: Algorithm Development Study.

JMIR medical informatics
BACKGROUND: Diabetic retinopathy (DR) is the leading cause of preventable blindness worldwide. Machine learning (ML) systems can enhance DR in community-based screening. However, predictive power models for usability and performance are still being d...

Predicting cardiovascular outcomes in Chinese patients with type 2 diabetes by combining risk factor trajectories and machine learning algorithm: a cohort study.

Cardiovascular diabetology
BACKGROUND: Cardiovascular complications are major concerns for Chinese patients with type 2 diabetes. Accurately predicting these risks remains challenging due to limitations in traditional risk models. We aimed to develop a dynamic prediction model...

Improving stroke risk prediction by integrating XGBoost, optimized principal component analysis, and explainable artificial intelligence.

BMC medical informatics and decision making
The relevance of the study is due to the growing number of diseases of the cerebrovascular system, in particular stroke, which is one of the leading causes of disability and mortality in the world. To improve stroke risk prediction models in terms of...

Characterisation of cardiovascular disease (CVD) incidence and machine learning risk prediction in middle-aged and elderly populations: data from the China health and retirement longitudinal study (CHARLS).

BMC public health
BACKGROUND: Due to the ageing population and evolving lifestyles occurring in China, middle-aged and elderly populations have become high-risk groups for cardiovascular disease (CVD). The aim of this study was to analyse the incidence characteristics...

Machine learning-based plasma metabolomics for improved cirrhosis risk stratification.

BMC gastroenterology
BACKGROUND: Cirrhosis is a leading cause of mortality in patients with chronic liver disease (CLD). The rapid development of metabolomic technologies has enabled the capture of metabolic changes related to the progression of cirrhosis.

Machine Learning-Based Pediatric Early Warning Score: Patient Outcomes in a Pre- Versus Post-Implementation Study, 2019-2023.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
OBJECTIVES: To describe the deployment of pediatric Calculated Assessment of Risk and Triage (pCART), a machine learning (ML) model to predict the risk of the direct ward to the ICU transfer within 12 hours, and the associated improved outcomes among...

An Information Fusion System-Driven Deep Neural Networks With Application to Cancer Mortality Risk Estimate.

IEEE transactions on neural networks and learning systems
Next-generation sequencing (NGS) genomic data offer valuable high-throughput genomic information for computational applications in medicine. Using genomic data to identify disease-associated genes to estimate cancer mortality risk remains challenging...

Joint ensemble learning-based risk prediction of Alzheimer's disease among mild cognitive impairment patients.

The journal of prevention of Alzheimer's disease
OBJECTIVE: Due to the recognition for the importance of early intervention in Alzheimer's disease (AD), it is important to focus on prevention and treatment strategies for mild cognitive impairment (MCI). This study aimed to establish a risk predicti...