AIMC Topic: Risk Factors

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Comparative study of coronary artery disease prediction: conventional QRISK3 versus enhanced machine learning models combined with particle swarm optimisation algorithm.

Open heart
BACKGROUND: Coronary artery disease (CAD) is one of the biggest causes of mortality worldwide. Risk stratification for early detection is essential for the primary prevention of CAD. QRISK3 is known to overestimate future CAD risk in some populations...

Predictive value of systemic inflammation response index for atherosclerotic cardiovascular disease risk in patients with hypercholesterolemia: a machine learning study with dual-cohort validation.

Lipids in health and disease
BACKGROUND: Residual cardiovascular risk persists in patients with hypercholesterolemia despite lipid-lowering therapy, underscoring the importance of inflammation in ASCVD development. This study evaluated the relationship between Systemic Inflammat...

Multiple polygenic score approach in colorectal cancer risk prediction.

Scientific reports
Recent studies have demonstrated that for various diseases, incorporating polygenic risk scores (PRSs) for other traits and diseases into the PRS-based risk prediction model may improve predictive performance - known as Multiple Polygenic Score (MPS)...

Transparent AI-driven personalized risk prediction system for acute kidney injury after total hip arthroplasty.

Scientific reports
Acute kidney injury is a common and severe complication following total hip arthroplasty, particularly in elderly or high-risk patients with chronic conditions, significantly increasing morbidity and mortality rates. Traditional prediction methods of...

Machine learning integration of multi-modal radiomics and clinical factors predicts refracture risk after percutaneous kyphoplasty in postmenopausal women.

Scientific reports
This study explores the use of radiomic features extracted from preoperative T2-weighted MRI and CT images, combined with machine learning models, to predict the risk of vertebral refracture after percutaneous kyphoplasty (PKP) in postmenopausal wome...

Predicting hypertension and identifying most important factors among married women in Bangladesh using machine learning approach.

PloS one
INTRODUCTION: Hypertension is a leading contributor to maternal and cardiometabolic morbidity in Bangladesh. We developed and interpreted machine-learning (ML) models to predict hypertension and rank associated factors among married women with the go...

Non-linear association between Life's Essential 8 and diabetic retinopathy: mediating role of depression in US adults with diabetes.

BMC public health
BACKGROUND: Life's Essential 8 (LE8) is a comprehensive cardiovascular health (CVH) metric that is associated with chronic diseases. This study aimed to investigate the association between LE8 and diabetic retinopathy (DR) and the mediating role of d...

BRCAGenie: A machine learning-driven 43-gene polygenic risk score model for precision prediction of breast cancer survival.

Journal of translational medicine
BACKGROUND: Breast cancer is one of the most prevalent malignancies globally, imposing a substantial disease burden. Its inherent heterogeneity complicates prognosis and treatment, underscoring the need for accurate survival prediction models to guid...

Prognostic machine learning models for predicting postoperative complications following general surgery in Bandar Abbas, Iran: a study protocol.

BMJ open
INTRODUCTION: To enhance the quality of surgical care, complications need to be minimised. Consequently, comprehending the occurrence and risk elements for postoperative complications is essential. Subsequently, we will apply machine learning (ML) al...

Predicting COVID-19 patient recovery or mortality using deep neural decision tree and forest.

BMC research notes
OBJECTIVE: Identifying patients at high risk of mortality is crucial for emergency physicians to allocate hospital resources effectively, particularly in regions with limited medical services. This need becomes even more pressing during global health...