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Gene pathogenicity prediction of Mendelian diseases via the random forest algorithm.

Human genetics
The study of Mendelian diseases and the identification of their causative genes are of great significance in the field of genetics. The evaluation of the pathogenicity of genes and the total number of Mendelian disease genes are both important questi...

Predicting breast cancer metastasis by using serum biomarkers and clinicopathological data with machine learning technologies.

International journal of medical informatics
BACKGROUND: Approximately 10%-15% of patients with breast cancer die of cancer metastasis or recurrence, and early diagnosis of it can improve prognosis. Breast cancer outcomes may be prognosticated on the basis of surface markers of tumor cells and ...

Can machine learning predict resecability of a peritoneal carcinomatosis?

Surgical oncology
BACKGROUND: Approximately 20% of initially eligible patients in a HIPEC procedure eventually underwent a simple surgical exploration. These procedures are called 'open & close' (O & C) representing up to 48% of surgery. The objective of this study wa...

Prediction of hematoma expansion in spontaneous intracerebral hemorrhage using support vector machine.

EBioMedicine
BACKGROUND: Spontaneous intracerebral hemorrhage (ICH) is a devastating disease with high mortality rate. This study aimed to predict hematoma expansion in spontaneous ICH from routinely available variables by using support vector machine (SVM) metho...

Preoperative Prediction of Value Metrics and a Patient-Specific Payment Model for Primary Total Hip Arthroplasty: Development and Validation of a Deep Learning Model.

The Journal of arthroplasty
BACKGROUND: The primary objective was to develop and test an artificial neural network (ANN) that learns and predicts length of stay (LOS), inpatient charges, and discharge disposition for total hip arthroplasty. The secondary objective was to create...

Automated semantic labeling of pediatric musculoskeletal radiographs using deep learning.

Pediatric radiology
BACKGROUND: An automated method for identifying the anatomical region of an image independent of metadata labels could improve radiologist workflow (e.g., automated hanging protocols) and help facilitate the automated curation of large medical imagin...

Predicting coronary artery disease: a comparison between two data mining algorithms.

BMC public health
BACKGROUND: Cardiovascular diseases (CADs) are the first leading cause of death across the world. World Health Organization has estimated that morality rate caused by heart diseases will mount to 23 million cases by 2030. Hence, the use of data minin...

Artificial Neural Network Analysis of Spontaneous Preterm Labor and Birth and Its Major Determinants.

Journal of Korean medical science
BACKGROUND: Little research based on the artificial neural network (ANN) is done on preterm birth (spontaneous preterm labor and birth) and its major determinants. This study uses an ANN for analyzing preterm birth and its major determinants.

Deep Learning/Artificial Intelligence and Blood-Based DNA Epigenomic Prediction of Cerebral Palsy.

International journal of molecular sciences
The etiology of cerebral palsy (CP) is complex and remains inadequately understood. Early detection of CP is an important clinical objective as this improves long term outcomes. We performed genome-wide DNA methylation analysis to identify epigenomic...