AIMC Topic: Schizophrenia

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A Multidimensional Neural Maturation Index Reveals Reproducible Developmental Patterns in Children and Adolescents.

The Journal of neuroscience : the official journal of the Society for Neuroscience
Adolescence is a time of extensive neural restructuring, leaving one susceptible to atypical development. Although neural maturation in humans can be measured using functional and structural MRI, the subtle patterns associated with the initial stages...

DeepMiR2GO: Inferring Functions of Human MicroRNAs Using a Deep Multi-Label Classification Model.

International journal of molecular sciences
MicroRNAs (miRNAs) are a highly abundant collection of functional non-coding RNAs involved in cellular regulation and various complex human diseases. Although a large number of miRNAs have been identified, most of their physiological functions remain...

Integrating machining learning and multimodal neuroimaging to detect schizophrenia at the level of the individual.

Human brain mapping
Schizophrenia is a severe psychiatric disorder associated with both structural and functional brain abnormalities. In the past few years, there has been growing interest in the application of machine learning techniques to neuroimaging data for the d...

A review on neural network models of schizophrenia and autism spectrum disorder.

Neural networks : the official journal of the International Neural Network Society
This survey presents the most relevant neural network models of autism spectrum disorder and schizophrenia, from the first connectionist models to recent deep neural network architectures. We analyzed and compared the most representative symptoms wit...

Decentralized distribution-sampled classification models with application to brain imaging.

Journal of neuroscience methods
BACKGROUND: In this age of big data, certain models require very large data stores in order to be informative and accurate. In many cases however, the data are stored in separate locations requiring data transfer between local sites which can cause v...

Multivariate classification of schizophrenia and its familial risk based on load-dependent attentional control brain functional connectivity.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Patients with schizophrenia (SCZ), as well as their unaffected siblings (SIB), show functional connectivity (FC) alterations during performance of tasks involving attention. As compared with SCZ, these alterations are present in SIB to a lesser exten...

Use of Natural Language Processing to identify Obsessive Compulsive Symptoms in patients with schizophrenia, schizoaffective disorder or bipolar disorder.

Scientific reports
Obsessive and Compulsive Symptoms (OCS) or Obsessive Compulsive Disorder (OCD) in the context of schizophrenia or related disorders are of clinical importance as these are associated with a range of adverse outcomes. Natural Language Processing (NLP)...

Generalizability of machine learning for classification of schizophrenia based on resting-state functional MRI data.

Human brain mapping
Machine learning has increasingly been applied to classification of schizophrenia in neuroimaging research. However, direct replication studies and studies seeking to investigate generalizability are scarce. To address these issues, we assessed withi...