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Scleroderma, Systemic

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The role of klotho in systemic sclerosis.

Reumatismo
The aim was to evaluate the role of klotho in the pathogenesis of systemic sclerosis (SSc), through the measurement of its serum concentration in SSc patients compared to healthy controls, and to assess the association with cutaneous and visceral inv...

A Machine Learning Classifier for Assigning Individual Patients With Systemic Sclerosis to Intrinsic Molecular Subsets.

Arthritis & rheumatology (Hoboken, N.J.)
OBJECTIVE: High-throughput gene expression profiling of tissue samples from patients with systemic sclerosis (SSc) has identified 4 "intrinsic" gene expression subsets: inflammatory, fibroproliferative, normal-like, and limited. Prior methods require...

Rule-based and machine learning algorithms identify patients with systemic sclerosis accurately in the electronic health record.

Arthritis research & therapy
BACKGROUND: Systemic sclerosis (SSc) is a rare disease with studies limited by small sample sizes. Electronic health records (EHRs) represent a powerful tool to study patients with rare diseases such as SSc, but validated methods are needed. We devel...

Use of artificial intelligence in imaging in rheumatology - current status and future perspectives.

RMD open
After decades of basic research with many setbacks, artificial intelligence (AI) has recently obtained significant breakthroughs, enabling computer programs to outperform human interpretation of medical images in very specific areas. After this shock...