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Serum Albumin, Bovine

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Paper-based fluorescent immunoassay for highly sensitive and selective detection of norfloxacin in milk at picogram level.

Talanta
Norfloxacin (NOR) in milk may influence mammalian cell replication and bring about a decrease in the efficiency for treating infection in humans. However, current techniques for detecting NOR usually require expensive instruments and trained personne...

CMUT-based biosensor with convolutional neural network signal processing.

Ultrasonics
The improvement of the micromachined ultrasound transducer based (CMUT) biosensor fabrication technology and signal processing, which led to higher signal to noise ratio is reported. The biosensor contains interdigitally arranged CMUT structure with ...

Femtosecond laser programmed artificial musculoskeletal systems.

Nature communications
Natural musculoskeletal systems have been widely recognized as an advanced robotic model for designing robust yet flexible microbots. However, the development of artificial musculoskeletal systems at micro-nanoscale currently remains a big challenge,...

Carvacrol protects against carbonyl osmolyte-induced structural modifications and aggregation to serum albumin: Insights from physicochemical and molecular interaction studies.

International journal of biological macromolecules
The robust use of osmolytes (i.e., polyols and sugars) in the key therapeutic regimens/formulations has questioned their impact beyond the stability of therapeutic proteins as these osmolytes trigger structural alterations into proteins including mis...

Radial SERS acquisition on coffee ring for Serum-based breast cancer diagnosis through Multilayer Perceptron.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
The coffee-ring effect, involving spontaneous solute separation, has demonstrated promising potential in the context of patient serum analysis. In this study, an approach leveraging the coffee-ring-based analyte redistribution was developed for spect...

Spherical lesion formation in HIFU using robotic assistance for controlled focal point manipulation.

Scientific reports
We propose a robot-assisted method to generate spherical thermal lesions by high-intensity focused ultrasound (HIFU) ablation. Typically, HIFU-induced thermal lesions are cigar-shaped because the acoustic field in the focal area has a similar elongat...

Surface-Induced Unfolding Reveals Unique Structural Features and Enhances Machine Learning Classification Models.

Analytical chemistry
Native ion mobility-mass spectrometry combined with collision-induced unfolding (CIU) is a powerful analytical method for protein characterization, offering insights into structural stability and enabling the differentiation of analytes with similar ...

Machine Learning for Quantitative Prediction of Protein Adsorption on Well-Defined Polymer Brush Surfaces with Diverse Chemical Properties.

Langmuir : the ACS journal of surfaces and colloids
Polymer informatics has attracted increasing attention because machine learning can establish quantitative structure-property relationships in polymer materials. Understanding and controlling protein adsorption on polymer surfaces are crucial for var...

Single-Component Double-Emissive Ratiometric Probe: Toward Machine Learning Driven Detection and Discrimination of Neurological Biomarkers.

Analytical chemistry
This study presents an attractive single-component ratiometric fluorescent sensor that utilizes the oxidation of BSA-protected Au nanoclusters (BSA-Au NCs) by -Bromosuccinimide (NBS) to detect catecholamine neurotransmitters and their metabolites, wh...