AIMC Topic: Software

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Real-World evaluation of an AI triaging system for chest X-rays: A prospective clinical study.

European journal of radiology
Chest X-rays (CXRs) are crucial for diagnosing and managing lung conditions. While CXR is a common and cost-effective diagnostic tool, interpreting the high volume of CXRs is challenging due to workforce limitations. Artificial intelligence (AI) offe...

From Noise to Knowledge: Diffusion Probabilistic Model-Based Neural Inference of Gene Regulatory Networks.

Journal of computational biology : a journal of computational molecular cell biology
Understanding gene regulatory networks (GRNs) is crucial for elucidating cellular mechanisms and advancing therapeutic interventions. Original methods for GRN inference from bulk expression data often struggled with the high dimensionality and inhere...

Parameter optimization for stable clustering using FlowSOM: a case study from CyTOF.

Frontiers in immunology
High-dimensional cell phenotyping is a powerful tool to study molecular and cellular changes in health and diseases. CyTOF enables high-dimensional cell phenotyping using tens of surface and intra-cellular markers. To utilize the full potential of Cy...

Data flow in clinical laboratories: could metadata and peridata bridge the gap to new AI-based applications?

Clinical chemistry and laboratory medicine
In the last decades, clinical laboratories have significantly advanced their technological capabilities, through the use of interconnected systems and advanced software. Laboratory Information Systems (LIS), introduced in the 1970s, have transformed ...

Development of Machine Learning Copilot to Assist Novices in Learning Flexible Laryngoscopy.

The Laryngoscope
OBJECTIVES: Here we describe the development and pilot testing of the first artificial intelligence (AI) software "copilot" to help train novices to competently perform flexible fiberoptic laryngoscopy (FFL) on a mannikin and improve their uptake of ...

Stacking based ensemble learning framework for identification of nitrotyrosine sites.

Computers in biology and medicine
Protein nitrotyrosine is an essential post-translational modification that results from the nitration of tyrosine amino acid residues. This modification is known to be associated with the regulation and characterization of several biological function...

An AI Agent for Fully Automated Multi-Omic Analyses.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
With the fast-growing and evolving omics data, the demand for streamlined and adaptable tools to handle bioinformatics analysis continues to grow. In response to this need, Automated Bioinformatics Analysis (AutoBA) is introduced, an autonomous AI ag...

Automated orofacial virtual patient creation: A proof of concept.

Journal of dentistry
OBJECTIVES: To (1) construct a virtual patient (VP) using facial scan, intraoral scan, and low-dose computed tomography scab based on an Artificial intelligence (AI)-approach, (2) quantitatively compare it with AI-refined and semi-automatic registrat...

Machine learning optimized DriverDetect software for high precision prediction of deleterious mutations in human cancers.

Scientific reports
The detection of cancer-driving mutations is important for understanding cancer pathology and therapeutics development. Prediction tools have been created to streamline the computation process. However, most tools available have heterogeneous sensiti...