AIMC Topic: Spinal Neoplasms

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Development of Machine Learning Algorithms for Prediction of 5-Year Spinal Chordoma Survival.

World neurosurgery
BACKGROUND: Chordomas are locally invasive slow-growing tumors that are difficult to study because of the rarity of the tumors and the lack of significant volumes of patients with longitudinal follow-up. As such, there are currently no machine learni...

Deep convolutional neural network-based segmentation and classification of difficult to define metastatic spinal lesions in 3D CT data.

Medical image analysis
This paper aims to address the segmentation and classification of lytic and sclerotic metastatic lesions that are difficult to define by using spinal 3D Computed Tomography (CT) images obtained from highly pathologically affected cases. As the lesion...

A multi-resolution approach for spinal metastasis detection using deep Siamese neural networks.

Computers in biology and medicine
Spinal metastasis, a metastatic cancer of the spine, is the most common malignant disease in the spine. In this study, we investigate the feasibility of automated spinal metastasis detection in magnetic resonance imaging (MRI) by using deep learning ...

Inverse treatment planning for spinal robotic radiosurgery: an international multi-institutional benchmark trial.

Journal of applied clinical medical physics
Stereotactic radiosurgery (SRS) is the accurate, conformal delivery of high-dose radiation to well-defined targets while minimizing normal structure doses via steep dose gradients. While inverse treatment planning (ITP) with computerized optimization...

Improving Computer-Aided Detection Using Convolutional Neural Networks and Random View Aggregation.

IEEE transactions on medical imaging
Automated computer-aided detection (CADe) has been an important tool in clinical practice and research. State-of-the-art methods often show high sensitivities at the cost of high false-positives (FP) per patient rates. We design a two-tiered coarse-t...

Zero-shot segmentation of spinal vertebrae with metastatic lesions: an analysis of Meta's Segment Anything Model 2 and factors affecting learning free segmentation.

Neurosurgical focus
OBJECTIVE: Accurate vertebral segmentation is an important step in imaging analysis pipelines for diagnosis and subsequent treatment of spinal metastases. Segmenting these metastases is especially challenging given their radiological heterogeneity. C...

A prospectively deployed deep learning-enabled automated quality assurance tool for oncological palliative spine radiation therapy.

The Lancet. Digital health
BACKGROUND: Palliative spine radiation therapy is prone to treatment at the wrong anatomic level. We developed a fully automated deep learning-based spine-targeting quality assurance system (DL-SpiQA) for detecting treatment at the wrong anatomic lev...

Predicting 90-Day and 1-Year Mortality in Spinal Metastatic Disease: Development and Internal Validation.

Neurosurgery
BACKGROUND: Increasing prevalence of metastatic disease has been accompanied by increasing rates of surgical intervention. Current tools have poor to fair predictive performance for intermediate (90-d) and long-term (1-yr) mortality.

Development of Machine Learning Algorithms for Prediction of 30-Day Mortality After Surgery for Spinal Metastasis.

Neurosurgery
BACKGROUND: Preoperative prognostication of short-term postoperative mortality in patients with spinal metastatic disease can improve shared decision making around end-of-life care.