AIMC Topic: Treatment Outcome

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Machine learning identifies immune-based biomarkers that predict efficacy of anti-angiogenesis-based therapies in advanced lung cancer.

International immunopharmacology
BACKGROUND: The anti-angiogenic drugs showed remarkable efficacy in the treatment of lung cancer. Nonetheless, the potential roles of the intra-tumoral immune cell abundances and peripheral blood immunological features in prognosis prediction of pati...

Anti-VEGF treatment outcome prediction based on optical coherence tomography images in neovascular age-related macular degeneration using a deep neural network.

Scientific reports
Age-related macular degeneration (AMD) is a major cause of blindness in developed countries, and the number of affected patients is increasing worldwide. Intravitreal injections of anti-vascular endothelial growth factor (VEGF) are the standard thera...

Random Forest Prognostication of Survival and 6-Month Outcome in Pediatric Patients Following Decompressive Craniectomy for Traumatic Brain Injury.

World neurosurgery
BACKGROUND: There is a dearth of literature regarding prognostic and predictive factors for outcome following pediatric decompressive craniectomy (DC) performed after traumatic brain injury (TBI). The aim of this study was to develop a random forest ...

Predictors for improvement in personality functioning during outpatient psychotherapy: A machine learning approach within a psychodynamic psychotherapy sample.

European psychiatry : the journal of the Association of European Psychiatrists
BACKGROUND: Since its introduction in the diagnostic manuals DSM-5 and ICD-11, the construct of personality functioning has gained increasing attention. However, it remains unclear which factors might predict improvement in personality functioning.

Use of machine learning to identify prognostic variables for outcomes in chronic low back pain treatment: a retrospective analysis.

The Journal of manual & manipulative therapy
OBJECTIVES: Most patients seen in physical therapy (PT) clinics for low back pain (LBP) are treated for chronic low back pain (CLBP), yet PT interventions suggest minimal effectiveness. The Cochrane Back Review Group proposed 'Holy Grail' questions, ...

Early and noninvasive prediction of response to neoadjuvant therapy for breast cancer via longitudinal ultrasound and MR deep learning: A multicentre study.

Academic radiology
RATIONALE AND OBJECTIVES: The early prediction of response to neoadjuvant chemotherapy (NAC) will aid in the development of personalized treatments for patients with breast cancer. This study investigated the value of longitudinal multimodal deep lea...

The established of a machine learning model for predicting the efficacy of adjuvant interferon alpha1b in patients with advanced melanoma.

Frontiers in immunology
BACKGROUND: Interferon-alpha1b (IFN-α1b) has shown remarkable therapeutic potential as adjuvant therapy for melanoma. This study aimed to develop five machine learning models to evaluate the efficacy of postoperative IFN-α1b in patients with advanced...

Impact of upper extremity robotic rehabilitation on respiratory parameters, functional capacity and dyspnea in patients with stroke: a randomized controlled study.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
BACKGROUND: Stroke leads to reduced mobility and functional capacity, also negatively affects respiratory functions and muscle strength.