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Treatment Outcome

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Comprehensive clinical scale-based machine learning model for predicting subthalamic nucleus deep brain stimulation outcomes in Parkinson's disease.

Neurosurgical review
Parkinson's Disease (PD) is a growing burden with varied clinical manifestations and responses to Subthalamic Nucleus Deep Brain Stimulation (STN-DBS). At present, there is no effective and simple machine learning model based on comprehensive clinica...

Inductive reasoning with large language models: A simulated randomized controlled trial for epilepsy.

Epilepsy research
INTRODUCTION: To investigate the potential of using artificial intelligence (AI), specifically large language models (LLMs), for synthesizing information in a simulated randomized clinical trial (RCT) for an anti-seizure medication, cenobamate, demon...

Application of causal forests to randomised controlled trial data to identify heterogeneous treatment effects: a case study.

BMC medical research methodology
BACKGROUND: Classical approaches to subgroup analysis in randomised controlled trials (RCTs) to identify heterogeneous treatment effects (HTEs) involve testing the interaction between each pre-specified possible treatment effect modifier and the trea...

Machine Learning in Intravascular Ultrasound: Validating Automated Lesion Assessment for Complex Coronary Interventions.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
BACKGROUND: Intravascular ultrasound (IVUS) is essential for assessing complex coronary lesions, but remains underutilized in part due to difficulties in image interpretation. The AVVIGO IVUS Automated Lesion Assessment (ALA) software, which uses mac...

An Integrative Machine Learning Model for Predicting Early Safety Outcomes in Patients Undergoing Transcatheter Aortic Valve Implantation.

Medicina (Kaunas, Lithuania)
: Early safety outcomes following transcatheter aortic valve implantation (TAVI) for severe aortic stenosis are critical for patient prognosis. Accurate prediction of adverse events can enhance patient management and improve outcomes. : This study ai...

Robotic beds for the treatment of positional obstructive sleep apnea - A randomized cross-over pilot trial.

Sleep medicine
BACKGROUND: Interventions leading to avoidance of supine position and thus reducing the likelihood of upper airway collapse during sleep are a treatment approach for positional obstructive sleep apnea (POSA). The aim of this randomized cross-over tri...

Clinical efficacy of NIBS in enhancing neuroplasticity for stroke recovery.

Journal of neuroscience methods
BACKGROUND: For stroke patients, a therapeutic approach named Non-invasive brain stimulation (NIBS) was applied and it has gained attention. This NIBS approach enhances the neuroplasticity and facilitates in functional Stroke Rehabilitation (SR) thro...

Prediction of tuberculosis treatment outcomes using biochemical makers with machine learning.

BMC infectious diseases
BACKGROUND: Tuberculosis (TB) continues to pose a significant threat to global public health. Enhancing patient prognosis is essential for alleviating the disease burden.

Machine learning for predicting outcomes of transcatheter aortic valve implantation: A systematic review.

International journal of medical informatics
BACKGROUND: Transcatheter aortic valve implantation (TAVI) therapy has demonstrated its clear benefits such as low invasiveness, to treat aortic stenosis. Despite associated benefits, still post-procedural complications might occur. The severity of t...