AIMC Topic: Vitamin D

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Cohort profile: Japanese human milk study, a prospective birth cohort: baseline data for lactating women, infants and human milk macronutrients.

BMJ open Dec 30, 2021
PURPOSE: The Japanese Human Milk Study, a longitudinal prospective cohort study, was set up to clarify how maternal health, nutritional status, lifestyle and sociodemographic and economic factors affect breastfeeding practices and human milk composit...
Fatty Acids Humans Carbohydrates Child Prospective Studies Cesarean Section Japan Phospholipids Milk, Human Pregnancy Male Lactation Vitamin D Infant Female Breast Feeding Osteopontin Cohort Studies Nutrients
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Prognostic Value of Vitamin D Serum Levels in Cutaneous Melanoma.

Actas dermo-sifiliograficas Nov 16, 2021
INTRODUCTION: Vitamin D plays a fundamental role in many metabolic pathways, including those involved in cell proliferation and the immune response. Serum levels of this vitamin have been linked to melanoma risk and prognosis. This study aimed to ass...
Prognosis Retrospective Studies Melanoma Skin Neoplasms Humans Vitamin D Vitamins Melanoma, Cutaneous Malignant
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Identification of kinase inhibitors that rule out the CYP27B1-mediated activation of vitamin D: an integrated machine learning and structure-based drug designing approach.

Molecular diversity Jul 16, 2021
CYP27B1, a cytochrome P450-containing hydroxylase enzyme, converts vitamin D precursor calcidiol (25-hydroxycholecalciferol) to its active form calcitriol (1α,25(OH)D). Tyrosine kinase inhibitor such as imatinib is reported to interfere with the acti...
Support Vector Machine Vitamin D 25-Hydroxyvitamin D3 1-alpha-Hydroxylase Structure-Activity Relationship Humans Machine Learning Small Molecule Libraries Animals Metabolic Networks and Pathways Enzyme Inhibitors Neural Networks, Computer Algorithms Models, Molecular Databases, Pharmaceutical Binding Sites Reproducibility of Results Molecular Docking Simulation Phosphotransferases Molecular Dynamics Simulation Drug Design Amino Acid Sequence Protein Binding
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Prevalence of and Risk Factors for Hypovitaminosis D in Patients with Rotator Cuff Tears.

Clinics in orthopedic surgery Dec 21, 2020
BACKGROUD: It has been reported that vitamin D may play an important role in rotator cuff tears. However, there has been limited information about the prevalence of and risk factors for hypovitaminosis D in patients with rotator cuff tears. Therefore...
Age Factors Sex Factors Rotator Cuff Injuries Middle Aged Prevalence Vitamin D Retrospective Studies Vitamin D Deficiency Humans Risk Factors Aged Aged, 80 and over Adult
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Update on benign paroxysmal positional vertigo.

Journal of neurology Nov 24, 2020
Benign paroxysmal positional vertigo (BPPV) is the most common cause of vertigo worldwide. This review considers recent advances in the diagnosis and management of BPPV including the use of web-based technology and artificial intelligence as well as ...
Artificial Intelligence Vitamin D Dietary Supplements Humans Benign Paroxysmal Positional Vertigo
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Relation of vitamin D and BsmI variant with temporomandibular diseases in the Turkish population.

The British journal of oral & maxillofacial surgery Aug 28, 2020
Vitamin D (VD) levels and several variants in the vitamin D receptor (VDR) gene are associated with the occurrence of diseases of the bones and cartilage. The aim of this research was to study and compare the association of the BsmI variant in the VD...
Case-Control Studies Genetic Predisposition to Disease Genotype Vitamin D Alleles Receptors, Calcitriol Temporomandibular Joint Disorders Humans
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Alendronate/Vitamin D for attenuating bone mineral density loss during antiretroviral initiation: a pilot randomized controlled trial.

HIV research & clinical practice Feb 27, 2020
Antiretroviral therapy (ART) initiation is associated with decreases in bone mineral density (BMD). To plan for a larger trial, we sought to obtain preliminary estimates for the difference in the change in BMD at 48 weeks achieved with 24 weeks of p...
Anti-Retroviral Agents Alendronate Bone Density Conservation Agents HIV Infections Canada Vitamin D Humans CD4 Lymphocyte Count Bone Density Young Adult Female Adult Male Pilot Projects
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Vitamin D insufficiency is associated with subclinical atherosclerosis in HIV-1-infected patients on combination antiretroviral therapy.

HIV research & clinical practice Feb 17, 2020
Vitamin D insufficiency has been associated with faster progression of atherosclerosis and increased cardiovascular disease risk, but limited data are available in HIV-infected people. So, we examined potential correlation between vitamin D status a...
Vitamin D Vitamin D Deficiency Atherosclerosis Anti-Retroviral Agents Cross-Sectional Studies Male Middle Aged HIV Infections Drug Therapy, Combination Carotid Intima-Media Thickness Humans Retrospective Studies Female Risk Factors Adult
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Genetic Variation in Cytochrome P450 2R1 and Vitamin D Binding Protein Genes are associated with Vitamin D Deficiency in Adolescents.

International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition Nov 15, 2019
Genome Wide Association Studies (GWAS) have evaluated several genes related to vitamin D synthesis, metabolism and transport. They have proposed a genetic basis for low levels of vitamin D in the blood. The current study aims to investigate the rela...
Humans Female Vitamin D Deficiency Iran Genetic Predisposition to Disease Male Cytochrome P450 Family 2 Cholestanetriol 26-Monooxygenase Polymorphism, Single Nucleotide Case-Control Studies Vitamin D-Binding Protein Cytochrome P-450 Enzyme System Adolescent Genotype Genome-Wide Association Study Vitamin D
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Directional Relationship Between Vitamin D Status and Prediabetes: A New Approach from Artificial Neural Network in a Cohort of Workers with Overweight-Obesity.

Journal of the American College of Nutrition Apr 25, 2019
Despite the increasing literature on the association of diabetes with inflammation, cardiovascular risk, and vitamin D (25(OH)D) concentrations, strong evidence on the direction of causality among these factors is still lacking. This gap could be ad...
Retrospective Studies Female Aged Adult Male Humans Neural Networks, Computer Vitamin D Deficiency Middle Aged Data Mining Cohort Studies Prediabetic State Overweight Vitamin D
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