Annals of oncology : official journal of the European Society for Medical Oncology
Sep 29, 2021
BACKGROUND: The Nottingham histological grade (NHG) is a well-established prognostic factor for breast cancer that is broadly used in clinical decision making. However, ∼50% of patients are classified as grade 2, an intermediate risk group with low c...
Annals of oncology : official journal of the European Society for Medical Oncology
Jun 15, 2021
BACKGROUND: Clinical management of soft tissue sarcoma (STS) is particularly challenging. Here, we used digital pathology and deep learning (DL) for diagnosis and prognosis prediction of STS.
Annals of oncology : official journal of the European Society for Medical Oncology
Apr 15, 2020
BACKGROUND: Preoperative evaluation of the number of lymph node metastasis (LNM) is the basis of individual treatment of locally advanced gastric cancer (LAGC). However, the routinely used preoperative determination method is not accurate enough.
Annals of oncology : official journal of the European Society for Medical Oncology
Jun 1, 2019
INTRODUCTION: Immunotherapy is regarded as one of the major breakthroughs in cancer treatment. Despite its success, only a subset of patients responds-urging the quest for predictive biomarkers. We hypothesize that artificial intelligence (AI) algori...
Annals of oncology : official journal of the European Society for Medical Oncology
Aug 1, 2018
BACKGROUND: Deep learning convolutional neural networks (CNN) may facilitate melanoma detection, but data comparing a CNN's diagnostic performance to larger groups of dermatologists are lacking.
Annals of oncology : official journal of the European Society for Medical Oncology
Apr 1, 2018
BACKGROUND: Tumor-specific mutations form novel immunogenic peptides called neoantigens. Neoantigens can be used as a biomarker predicting patient response to cancer immunotherapy. Although a predicted binding affinity (IC50) between peptide and majo...