AI Medical Compendium Journal:
Diagnostic microbiology and infectious disease

Showing 11 to 20 of 20 articles

In vitro activity of flomoxef against extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Korea.

Diagnostic microbiology and infectious disease Nov 26, 2018
To find an alternative regimen for the treatment of extended-spectrum β-lactamase (EBSL)-producing Enterobacteriaceae infections, we examined the in vitro activity of flomoxef against Escherichia coli and Klebsiella pneumoniae having CTX-M-1 group an...
beta-Lactamases Klebsiella pneumoniae Humans Hospitals, University Cephalosporins Klebsiella Infections Anti-Bacterial Agents Escherichia coli Proteins Escherichia coli Microbial Sensitivity Tests Korea Escherichia coli Infections
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Plasma and cerebrospinal fluid population pharmacokinetic modeling and simulation of meropenem after intravenous and intrathecal administration in postoperative neurosurgical patients.

Diagnostic microbiology and infectious disease Aug 17, 2018
Combined intravenous and local intrathecal administration of meropenem in patients after craniotomy is widely used to treat intracranial infections. However, the optimal dosing regimen of meropenem has not been investigated, posing a risk to treatmen...
Time Factors Cerebrospinal Fluid Neurosurgical Procedures Surgical Wound Infection Humans Female Plasma Anti-Bacterial Agents Meropenem Male Administration, Intravenous Microbial Sensitivity Tests Administration, Inhalation Beijing
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In vitro activity of eravacycline against 2213 Gram-negative and 2424 Gram-positive bacterial pathogens isolated in Canadian hospital laboratories: CANWARD surveillance study 2014-2015.

Diagnostic microbiology and infectious disease Dec 22, 2017
Gram-negative (n=2213) and Gram-positive (n=2424) pathogens isolated from patients in 13 Canadian hospitals in 2014 and 2015 were tested for in vitro susceptibility to eravacycline and comparators using the Clinical and Laboratory Standards Institute...
Microbial Sensitivity Tests Canada Enterobacteriaceae Gram-Negative Bacteria Gram-Positive Bacteria Gram-Positive Bacterial Infections Enterobacteriaceae Infections Epidemiological Monitoring Humans Anti-Bacterial Agents Gram-Negative Bacterial Infections Laboratories, Hospital Tetracyclines
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Surveillance of iclaprim activity: In vitro susceptibility of gram-positive pathogens collected from 2012 to 2014 from the United States, Asia Pacific, Latin American and Europe.

Diagnostic microbiology and infectious disease Dec 7, 2017
Iclaprim is a diaminopyrimidine, which inhibits bacterial dihydrofolate reductase, and it is highly active against Gram-positive pathogens including emerging drug-resistant pathogens. In vitro activity of iclaprim and comparators against 2814 Gram-po...
Europe Gram-Positive Bacterial Infections Pyrimidines Americas Asia Folic Acid Antagonists Streptococcus Humans Anti-Bacterial Agents Microbial Sensitivity Tests Staphylococcus aureus
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Evaluation of a human adenovirus viral load assay using the Altona RealStar® PCR test.

Diagnostic microbiology and infectious disease Dec 2, 2017
This study evaluated the performance of the Altona Diagnostics RealStar® Adenovirus Research Use Only (RUO) real-time PCR reagents for HAdV quantitation in plasma samples from immunodeficient patients. The assay was linear from 2.30-9.17 log copies/m...
Adenovirus Infections, Human Adenoviruses, Human Viral Load Polymerase Chain Reaction Plasma Humans Prospective Studies Reproducibility of Results
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Determination of Tedizolid susceptibility interpretive criteria for gram-positive pathogens according to clinical and laboratory standards institute guidelines.

Diagnostic microbiology and infectious disease Nov 7, 2017
For effective antibacterial therapy, physicians require qualitative test results using susceptibility breakpoints provided by clinical microbiology laboratories. This article summarizes the key components used to establish the Clinical Laboratory Sta...
Humans Mice Staphylococcus aureus Streptococcus agalactiae Streptococcus pyogenes Anti-Bacterial Agents Animals Microbial Sensitivity Tests Tetrazoles Linezolid Enterococcus faecalis Bacterial Load Gram-Positive Bacterial Infections Oxazolidinones
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Antimicrobial activity of ceftazidime-avibactam and comparator agents when tested against bacterial isolates causing infection in cancer patients (2013-2014).

Diagnostic microbiology and infectious disease Nov 29, 2016
We evaluated the antimicrobial susceptibility of 623 Gram-negative organisms causing infection in patients with cancer in 52 United States hospitals (2013-2014) as part of the International Network for Optimal Resistance Monitoring (INFORM) program. ...
Klebsiella pneumoniae Drug Combinations Escherichia coli beta-Lactamases Neoplasms Microbial Sensitivity Tests Drug Resistance, Multiple, Bacterial Amikacin Azabicyclo Compounds Ceftazidime Thienamycins Pseudomonas aeruginosa Meropenem Colistin Enterobacter cloacae Humans Anti-Bacterial Agents
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Establishing the validity of different susceptibility testing methods to evaluate the in vitro activity of amoxicillin-clavulanate against Escherichia coli.

Diagnostic microbiology and infectious disease Dec 17, 2015
Amoxicillin-clavulanate MICs of 160 Escherichia coli isolates with characterized resistance mechanisms were obtained by 2 MIC gradient strip brands, 3 automated systems, and reference ISO microdilution method using EUCAST (fixed 2μg/mL clavulanate) a...
Amoxicillin-Potassium Clavulanate Combination Anti-Bacterial Agents Microbial Sensitivity Tests Escherichia coli
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In vitro activities and detection performances of cefmetazole and flomoxef for extended-spectrum β-lactamase and plasmid-mediated AmpC β-lactamase-producing Enterobacteriaceae.

Diagnostic microbiology and infectious disease Dec 11, 2015
To investigate the in vitro activities of cephamycins (cefmetazole and flomoxef) for extended-spectrum β-lactamase (ESBL)- and plasmid-mediated AmpC β-lactamase (pAmpC)-producing Enterobacteriaceae, a total of 574 third-generation cephalosporin-resis...
Cefmetazole Genotype Sequence Analysis, DNA beta-Lactam Resistance beta-Lactamases Japan Enterobacteriaceae Cephalosporins Polymerase Chain Reaction Enterobacteriaceae Infections Humans Anti-Bacterial Agents Microbial Sensitivity Tests
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Organism burden, toxin concentration, and lactoferrin concentration do not distinguish between clinically significant and nonsignificant diarrhea in patients with Clostridium difficile.

Diagnostic microbiology and infectious disease Nov 30, 2015
Clostridium difficile infection is often overdiagnosed in patients with mild diarrhea. We evaluated 4 biomarkers as surrogates for clinically significant diarrhea (≥ 3 episodes in 24 hours) in 59 PCR-positive patients with and 59 PCR-positive patient...
Female Male Middle Aged Severity of Illness Index Humans Bacterial Load Case-Control Studies Clostridium Infections Diarrhea Bacterial Toxins Feces Clostridioides difficile Lactoferrin
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