Much of the controversy evoked by the use of deep neural networks as models of biological neural systems amount to debates over what constitutes scientific progress in neuroscience. To discuss what constitutes scientific progress, one must have a goa...
A common pitfall of current reinforcement learning agents implemented in computational models is in their inadaptability postoptimization. Najarro and Risi [Najarro E, Risi S. . 2020: 20719-20731, 2020] demonstrate how such adaptability may be salvag...
Four recent articles were examined for their use of resting-state functional magnetic resonance imaging on participants with posttraumatic symptoms. Theory-driven computations were complemented by the novel use of network metrics, which revealed redu...
Modern neurophysiology research requires the interrogation of high-dimensionality data sets. Machine learning and artificial intelligence (ML/AI) workflows have permeated into nearly all aspects of daily life in the developed world but have not been ...
Robotic transcranial magnetic stimulation (TMS) is a noninvasive and safe tool that produces cortical motor maps using neuronavigational and neuroanatomical images. Motor maps are individualized representations of the primary motor cortex (M1) topogr...
The cere resembles a feedforward, three-layer network of neurons in which the "hidden layer" consists of Purkinje cells (P-cells) and the output layer consists of deep cerebellar nucleus (DCN) neurons. In this analogy, the output of each DCN neuron i...
To isolate brain activity that may reflect effective cognitive processes during the study phase of a memory task, cognitive neuroscientists commonly contrast brain activity during study of later-remembered versus later-forgotten items. This "subseque...
One of the most powerful excitatory synapses in the brain is formed by cerebellar climbing fibers, originating from neurons in the inferior olive, that wrap around the proximal dendrites of cerebellar Purkinje cells. The activation of a single olivar...
This study quantified eight small-molecule neurotransmitters collected simultaneously from prefrontal cortex of C57BL/6J mice ( = 23) during wakefulness and during isoflurane anesthesia (1.3%). Using isoflurane anesthesia as an independent variable e...
The Wilson-Cowan equations represent a landmark in the history of computational neuroscience. Along with the insights Wilson and Cowan offered for neuroscience, they crystallized an approach to modeling neural dynamics and brain function. Although th...