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Acetylcholine

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Peroxidase-like activity of acetylcholine-based colorimetric detection of acetylcholinesterase activity and an organophosphorus inhibitor.

Journal of materials chemistry. B
Colorimetric detection of acetylcholinesterase (AChE) and its inhibitor organophosphates (OPs) is attractive for its convenience, but the addition of exogenous catalyst to produce a chromogenic agent may result in complexity and interference. Herein,...

Influence of Nanosilver on Endothelial Function and Vascular Reactivity of Isolated Rabbit Carotid Artery.

Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria
There is paucity of information on the effects and mechanism of action of Nanosilver on vascular tone andendothelial function in spite of the upsurge in nanotechnology application in biomedicine. The present study determined theeffect of Nanosilver o...

Deep learning of spontaneous arousal fluctuations detects early cholinergic defects across neurodevelopmental mouse models and patients.

Proceedings of the National Academy of Sciences of the United States of America
Neurodevelopmental spectrum disorders like autism (ASD) are diagnosed, on average, beyond age 4 y, after multiple critical periods of brain development close and behavioral intervention becomes less effective. This raises the urgent need for quantita...

Modeling uncertainty-seeking behavior mediated by cholinergic influence on dopamine.

Neural networks : the official journal of the International Neural Network Society
Recent findings suggest that acetylcholine mediates uncertainty-seeking behaviors through its projection to dopamine neurons - another neuromodulatory system known for its major role in reinforcement learning and decision-making. In this paper, we pr...

Neurotransmitter networks in mouse prefrontal cortex are reconfigured by isoflurane anesthesia.

Journal of neurophysiology
This study quantified eight small-molecule neurotransmitters collected simultaneously from prefrontal cortex of C57BL/6J mice ( = 23) during wakefulness and during isoflurane anesthesia (1.3%). Using isoflurane anesthesia as an independent variable e...

Spiking Neural P Systems With Enzymes.

IEEE transactions on nanobioscience
The neurotransmitter is a chemical substance that transmits information between neurons. Its metabolic process includes four links: synthesis, storage, release and inactivation. As one of the important chemical components of neurotransmitters, acetyl...