Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Oct 22, 2019
INTRODUCTION: Adequate head and neck (HN) organ-at-risk (OAR) delineation is crucial for HN radiotherapy and for investigating the relationships between radiation dose to OARs and radiation-induced side effects. The automatic contouring algorithms th...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Oct 17, 2019
BACKGROUND AND PURPOSE: Manual contouring is labor intensive, and subject to variations in operator knowledge, experience and technique. This work aims to develop an automated computed tomography (CT) multi-organ segmentation method for prostate canc...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Aug 17, 2019
BACKGROUND AND PURPOSE: Integrated analysis of existing radiosensitivity data obtained by the gold-standard clonogenic assay has the potential to improve our understanding of cancer cell radioresistance. However, extraction of radiosensitivity data f...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Jul 11, 2019
BACKGROUND AND PURPOSE: To investigate a novel markerless prostate localization strategy using a pre-trained deep learning model to interpret routine projection kilovoltage (kV) X-ray images in image-guided radiation therapy (IGRT).
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Jul 11, 2019
PURPOSE: Glioblastoma is routinely treated by concomitant radiochemotherapy. Current target definition guidelines use anatomic MRI (magnetic resonance imaging) scans, taking into account contrast enhancement and the rather unspecific hyperintensity o...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
May 27, 2019
PURPOSE/OBJECTIVE: Precise delineation of organs at risk (OARs) in head and neck cancer (HNC) is necessary for accurate radiotherapy. Although guidelines exist, significant interobserver variability (IOV) remains. The aim was to validate a 3D convolu...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Apr 11, 2019
PURPOSE: This study assessed the dosimetric accuracy of synthetic CT images generated from magnetic resonance imaging (MRI) data for focal brain radiation therapy, using a deep learning approach.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Jan 23, 2019
BACKGROUND AND PURPOSE: Radiation pneumonitis (RP) is a radiotherapy dose-limiting toxicity for locally advanced non-small cell lung cancer (LA-NSCLC). Prior studies have proposed relevant dosimetric constraints to limit this toxicity. Using machine ...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Dec 31, 2018
BACKGROUND AND PURPOSE: Intensity-modulated radiation therapy (IMRT) is currently indicated to treat anal squamous cell carcinoma (ASCC). Conformal dose delivery and steep dose gradients may cause marginal misses. We analyzed patterns of locoregional...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Dec 31, 2018
Radiomics - The extraction of quantitative features from radiologic images - shows increasing potential in contributing to modern personalized medicine approaches. MITK Phenotyping is an openly distributed radiomics framework implementing an exhausti...