AI Medical Compendium Journal:
Translational psychiatry

Showing 1 to 10 of 47 articles

Personalized prediction of negative affect in individuals with serious mental illness followed using long-term multimodal mobile phenotyping.

Translational psychiatry
Heightened negative affect is a core feature of serious mental illness. Over 90% of American adults own a smartphone, equipped with an array of sensors which can continuously and unobtrusively measure behaviors (e.g., activity levels, location, and p...

COMPASS: Computational mapping of patient-therapist alliance strategies with language modeling.

Translational psychiatry
The therapeutic working alliance is a critical predictor of psychotherapy success. Traditionally, working alliance assessment relies on questionnaires completed by both therapists and patients. In this paper, we present COMPASS, a novel framework to ...

Predictive modeling of response to repetitive transcranial magnetic stimulation in treatment-resistant depression.

Translational psychiatry
Identifying predictors of treatment response to repetitive transcranial magnetic stimulation (rTMS) remain elusive in treatment-resistant depression (TRD). Leveraging electronic medical records (EMR), this retrospective cohort study applied supervise...

Decoding vital variables in predicting different phases of suicide among young adults with childhood sexual abuse: a machine learning approach.

Translational psychiatry
Young adults with childhood sexual abuse (CSA) are an especially vulnerable group to suicide. Suicide encompasses different phases, but for CSA survivors the salient factors precipitating suicide are rarely studied. In this study, from a progressive ...

Machine learning-based differentiation of schizophrenia and bipolar disorder using multiscale fuzzy entropy and relative power from resting-state EEG.

Translational psychiatry
Schizophrenia (SZ) and bipolar disorder (BD) pose diagnostic challenges due to overlapping clinical symptoms and genetic factors, often resulting in misdiagnosis and suboptimal treatment outcomes. This study aimed to identify EEG-based biomarkers tha...

Neurofind: using deep learning to make individualised inferences in brain-based disorders.

Translational psychiatry
Within precision psychiatry, there is a growing interest in normative models given their ability to parse heterogeneity. While they are intuitive and informative, the technical expertise and resources required to develop normative models may not be a...

Leveraging OGTT derived metabolic features to detect Binge-eating disorder in individuals with high weight: a "seek out" machine learning approach.

Translational psychiatry
Binge eating disorder (BED) carries a 6 times higher risk for obesity and accounts for roughly 30% of type 2 diabetes cases. Timely identification of early glycemic disturbances and comprehensive treatment can impact on the likelihood of associated m...

Predicting antipsychotic responsiveness using a machine learning classifier trained on plasma levels of inflammatory markers in schizophrenia.

Translational psychiatry
We apply machine learning techniques to navigate the multifaceted landscape of schizophrenia. Our method entails the development of predictive models, emphasizing peripheral inflammatory biomarkers, which are classified into treatment response subgro...

Genome data based deep learning identified new genes predicting pharmacological treatment response of attention deficit hyperactivity disorder.

Translational psychiatry
Although the efficacy of pharmacy in the treatment of attention deficit/hyperactivity disorder (ADHD) has been well established, the lack of predictors of treatment response poses great challenges for personalized treatment. The current study employe...

Improving explainability of post-separation suicide attempt prediction models for transitioning service members: insights from the Army Study to Assess Risk and Resilience in Servicemembers - Longitudinal Study.

Translational psychiatry
Risk of U.S. Army soldier suicide-related behaviors increases substantially after separation from service. As universal prevention programs have been unable to resolve this problem, a previously reported machine learning model was developed using pre...