AIMC Topic: Adenocarcinoma

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Integrating multiomics analysis and machine learning to refine the molecular subtyping and prognostic analysis of stomach adenocarcinoma.

Scientific reports
Stomach adenocarcinoma (STAD) is a common malignancy with high heterogeneity and a lack of highly precise treatment options. We downloaded the multiomics data of STAD patients in The Cancer Genome Atlas (TCGA)-STAD cohort, which included mRNA, microR...

Machine learning classification and biochemical characteristics in the real-time diagnosis of gastric adenocarcinoma using Raman spectroscopy.

Scientific reports
This study aimed to identify biomolecular differences between benign gastric tissues (gastritis/intestinal metaplasia) and gastric adenocarcinoma and to evaluate the diagnostic power of Raman spectroscopy-based machine learning in gastric adenocarcin...

Assessment of different U-Net backbones in segmenting colorectal adenocarcinoma from H&E histopathology.

Pathology, research and practice
Adenocarcinoma, the most prevalent type of colorectal cancer, makes up roughly 95 % of all cases and is associated with a notably high mortality rate. Owing to the various risk factors which might include personal choices and habits or genetic factor...

Hepatoid adenocarcinoma of the stomach with ideal response to neoadjuvant chemo-immunotherapy: a case report.

Frontiers in immunology
Hepatoid adenocarcinoma of the stomach (HAS) is a rare subtype of gastric cancer characterized by histological features resembling hepatocellular carcinoma. Surgical intervention remains the preferred treatment modality for eligible patients. However...

Deep learning-based prediction of HER2 status and trastuzumab treatment efficacy of gastric adenocarcinoma based on morphological features.

Journal of translational medicine
BACKGROUND: First-line treatment for advanced gastric adenocarcinoma (GAC) with human epidermal growth factor receptor 2 (HER2) is trastuzumab combined with chemotherapy. In clinical practice, HER2 positivity is identified through immunohistochemistr...

Evaluating the pathological and clinical implications of errors made by an artificial intelligence colon biopsy screening tool.

BMJ open gastroenterology
OBJECTIVE: Artificial intelligence (AI) tools for histological diagnosis offer great potential to healthcare, yet failure to understand their clinical context is delaying adoption. IGUANA (Interpretable Gland-Graphs using a Neural Aggregator) is an A...

Radiomics for differentiating adenocarcinoma and squamous cell carcinoma in non-small cell lung cancer beyond nodule morphology in chest CT.

Scientific reports
Distinguishing between primary adenocarcinoma (AC) and squamous cell carcinoma (SCC) within non-small cell lung cancer (NSCLC) tumours holds significant management implications. We assessed the performance of radiomics-based models in distinguishing ...

Analysis of diagnostic genes and molecular mechanisms of Crohn's disease and colon cancer based on machine learning algorithms.

Scientific reports
Crohn's disease (CD) is a chronic inflammatory bowel condition, and colon adenocarcinoma (COAD), as one of the most prevalent malignant tumors of the digestive tract, has been indicated by research to have a close association with CD. This study empl...

Machine learning-based prediction of duodenal stump leakage following laparoscopic gastrectomy for gastric cancer.

Surgery
BACKGROUND: Duodenal stump leakage is one of the most critical complications following gastrectomy surgery, with a high mortality rate. The present study aimed to establish a predictive model based on machine learning for forecasting the occurrence o...