AIMC Topic: Adolescent

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Accurate Paediatric Brain Tumour Classification Through Improved Quantitative Analysis of H MR Imaging and Spectroscopy.

NMR in biomedicine
Multimodality imaging is an emerging research topic in neuro-oncology for its potential of being able to demonstrate tumours in a more comprehensive manner. Diffusion-weighted magnetic resonance imaging (dMRI) and proton magnetic resonance spectrosco...

Machine learning-assisted tacrolimus dose optimization in childhood- onset systemic lupus erythematosus through population pharmacokinetic modeling.

Computers in biology and medicine
OBJECTIVE: This study aimed to improve treatment effectiveness in childhood-onset systemic lupus erythematosus (cSLE) by developing machine learning algorithms integrated with pharmacokinetic parameters to predict individualized tacrolimus dosing for...

Impact of environmental pollution on human health: Investigating the role of Polycyclic Aromatic Hydrocarbons in pediatric osteosarcoma.

Ecotoxicology and environmental safety
BACKGROUND: Polycyclic aromatic hydrocarbons (PAHs), widely emitted through industrial processes and vehicular exhaust, are recognized environmental carcinogens. Although PAH exposure has been linked to various malignancies, the specific molecular me...

Dosing prediction of valproic acid in pediatric patients with epilepsy: population pharmacokinetic model or machine learning model?

European journal of clinical pharmacology
PURPOSE: This study develops and compares population pharmacokinetics (PopPK) models and machine learning methods, including neural networks, to predict steady-state trough concentrations in pediatric patients and provide improved dosing recommendati...

A multidimensional prediction model for overtraining risk in youth soccer players: Integrating physiological and psychological markers.

Journal of sports sciences
Overtraining syndrome (OTS) poses a critical challenge in youth soccer, particularly during periods of rapid physiological maturation combined with high training demands. This study aimed to develop and validate a multidimensional prediction model fo...

Dynamic alterations of SEEG characteristics during peri-ictal period and localization of seizure onset zone.

Neurobiology of disease
BACKGROUND: The evolution in peri-ictal period (from pre-ictal to ictal phase) of seizures contains abundant epileptogenic information, which aids in exploring the mechanism of seizures and localizing the epileptogenic zone (EZ). This study aims to i...

Classification of epilepsy seizure types in pediatrics based on Turkish EEG reports.

Epilepsy research
This study focuses on the binary classification of pediatric epilepsy seizure types as focal or generalized using Turkish electroencephalography (EEG) reports, leveraging natural language processing (NLP) and machine learning methodologies. A novel d...

Diagnostic accuracy of an artificial intelligence-based platform in detecting periapical radiolucencies on cone-beam computed tomography scans of molars.

Journal of dentistry
OBJECTIVE: This study aimed to evaluate the diagnostic performance of an artificial intelligence (AI)-based platform (Diagnocat) in detecting periapical radiolucencies (PARLs) in cone-beam computed tomography (CBCT) scans of molars. Specifically, we ...

A Mixed-attention Network for Automated Interventricular Septum Segmentation in Bright-blood Myocardial T2* MRI Relaxometry in Thalassemia.

Academic radiology
RATIONALE AND OBJECTIVES: This study develops a deep-learning method for automatic segmentation of the interventricular septum (IS) in MR images to measure myocardial T2* and estimate cardiac iron deposition in patients with thalassemia.