AIMC Topic: Adult

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Factors involved in phenoconversion of CYP3A using 4β-hydroxycholesterol in stable kidney transplant recipients.

Pharmacological reports : PR
BACKGROUND: Phenoconversion is a phenomenon whereby some genotypic extensive metabolizers transiently exhibit drug metabolizing enzyme activity at similar level as that of poor metabolizers. Renal failure is known to decrease CYP3A activity in humans...

Alterations in muscle activation patterns during robot-assisted bilateral training: A pilot study.

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
Robot-assisted bilateral training is being developed as a new rehabilitation approach for stroke patients. However, there is still a lack of understanding of muscle functions when performing robot-assisted synchronous movements. The aim of this work ...

A neural network analysis of Lifeways cross-generation imputed data.

BMC research notes
OBJECTIVES: Neural networks are a powerful statistical tool that use nonlinear regression type models to obtain predictions. Their use in the Lifeways cross-generation study that examined body mass index (BMI) of children, among other measures, is ex...

A Machine Learning Approach to Reveal the NeuroPhenotypes of Autisms.

International journal of neural systems
Although much research has been undertaken, the spatial patterns, developmental course, and sexual dimorphism of brain structure associated with autism remains enigmatic. One of the difficulties in investigating differences between the sexes in autis...

A hierarchical machine learning classification approach for secondary task identification from observed driving behavior data.

Accident; analysis and prevention
According to NHTSA, more than 3477 people (including 551 non-occupants) were killed and 391,000 were injured due to distraction-related crashes in 2015. The distracted driving epidemic has long been under research to identify its impact on driving be...

A signature-based machine learning model for distinguishing bipolar disorder and borderline personality disorder.

Translational psychiatry
Mobile technologies offer new opportunities for prospective, high resolution monitoring of long-term health conditions. The opportunities seem of particular promise in psychiatry where diagnoses often rely on retrospective and subjective recall of mo...

Predicting instructed simulation and dissimulation when screening for depressive symptoms.

European archives of psychiatry and clinical neuroscience
The intentional distortion of test results presents a fundamental problem to self-report-based psychiatric assessment, such as screening for depressive symptoms. The first objective of the study was to clarify whether depressed patients like healthy ...

Analysis of Kidney Donation and Its Relationship With Graft Failure of the Recipient at 1 Year.

Transplantation proceedings
INTRODUCTION: Currently, the shortage of organs available for kidney transplantation and a change in donors' and recipients' profiles (elderly, with cardiovascular risk, donors after cardiac death), it is becoming necessary to assess grafts from expa...

Artificial Intelligence-Assisted Auscultation of Heart Murmurs: Validation by Virtual Clinical Trial.

Pediatric cardiology
Artificial intelligence (AI) has potential to improve the accuracy of screening for valvular and congenital heart disease by auscultation. However, despite recent advances in signal processing and classification algorithms focused on heart sounds, cl...