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Longitudinal antibody titers measured after COVID-19 mRNA vaccination can identify individuals at risk for subsequent infection.

Science translational medicine
A key issue in the post-COVID-19 pandemic era is the ongoing administration of COVID-19 vaccines. Repeated vaccination is essential for preparing against currently circulating and newly emerging severe acute respiratory syndrome coronavirus 2 (SARS-C...

Machine learning in sex estimation using CBCT morphometric measurements of canines.

Clinical oral investigations
OBJECTIVE: The aim of this study was to assess measurements of the maxillary canines using Cone Beam Computed Tomography (CBCT) and develop a machine learning model for sex estimation.

Development of a Recommendation Engine to University Student Mental Health Support Aligned With Stepped Care: Longitudinal Cohort Study.

Journal of medical Internet research
BACKGROUND: Mental health challenges are prevalent among Canadian higher education students, with significant rates of depression and anxiety often going untreated due to reduced early detection, stigmatizing beliefs, and practical barriers. The U-Fl...

Auto-Masked Audio Spectrogram Transformer for depression detection from speech.

Journal of affective disorders
BACKGROUND: Depression is a psychological disorder characterized by altered self-referential cognition and impaired emotional expression. Traditional diagnostic methods can be costly or intrusive, while Speech-based analysis offers an accessible alte...

From perceiving words to reading: Neural multivariate representations of sublexical vs. lexico-semantic processing during word-reading.

NeuroImage
While the neural underpinnings of semantic cognition have been extensively studied, the brain mechanisms that allow the extraction of meaning from the initially perceptual visual linguistic input are less understood. These mechanisms have typically b...

Interpretable Machine Learning for Predicting Adverse Pregnancy Outcomes in Gestational Diabetes: Retrospective Cohort Study.

JMIR medical informatics
BACKGROUND: Gestational diabetes mellitus (GDM) affects over 5% of pregnancies worldwide, elevating risks of type 2 diabetes post partum and complications such as fetal death, miscarriage, and congenital abnormalities. Effective GDM management is ess...

Practitioner Perspectives on the Uses of Generative AI Chatbots in Mental Health Care: Mixed Methods Study.

JMIR human factors
BACKGROUND: Generative artificial intelligence (AI) chatbots have the potential to improve mental health care for practitioners and clients. Evidence demonstrates that AI chatbots can assist with tasks such as documentation, research, counseling, and...

Using Wearable Device and Machine Learning to Predict Mood Symptoms in Bipolar Disorder: Development and Usability Study.

JMIR medical informatics
BACKGROUND: Bipolar disorder (BD) is a highly recurrent disorder. Early detection, early intervention, and prevention of recurrent bipolar mood symptoms are key to a better prognosis.

Real-Time Estimation of Arterial Partial Pressure of Carbon Dioxide in Patients Undergoing General Anesthesia: Predictive Modeling Study.

JMIR medical informatics
BACKGROUND: Adequate ventilation in mechanically ventilated patients is contingent upon the monitoring of the arterial partial pressure of carbon dioxide (PaCO2) during general anesthesia. Despite its significance, continuous monitoring remains chall...

Submovements Derived from Wearable Sensors Capture Ataxia Severity and Differ Across Motor Tasks and Directions of Motion.

Cerebellum (London, England)
Digital measures derived from wearable sensors are a promising approach for assessing motor impairment in clinical trials. Submovements, which are velocity curves extracted from time series data, have been successful in characterizing impaired moveme...