AIMC Topic: Aged, 80 and over
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Chronic Kidney Disease stratification using office visit records: Handling data imbalance via hierarchical meta-classification.
BMC medical informatics and decision making
Dec 12, 2018
BACKGROUND: Chronic Kidney Disease (CKD) is one of several conditions that affect a growing percentage of the US population; the disease is accompanied by multiple co-morbidities, and is hard to diagnose in-and-of itself. In its advanced forms it car...
Wrist accelerometer shape feature derivation methods for assessing activities of daily living.
BMC medical informatics and decision making
Dec 12, 2018
BACKGROUND: There has been an increasing interest in understanding the usefulness of wrist-based accelerometer data for physical activity (PA) assessment due to the ease of use and higher user compliance than other body placements. PA assessment stud...
Automated Abdominal Segmentation of CT Scans for Body Composition Analysis Using Deep Learning.
Radiology
Dec 11, 2018
Purpose To develop and evaluate a fully automated algorithm for segmenting the abdomen from CT to quantify body composition. Materials and Methods For this retrospective study, a convolutional neural network based on the U-Net architecture was traine...
Probiotic and selenium co-supplementation, and the effects on clinical, metabolic and genetic status in Alzheimer's disease: A randomized, double-blind, controlled trial.
Clinical nutrition (Edinburgh, Scotland)
Dec 10, 2018
BACKGROUND AND AIMS: Combined probiotic and selenium supplementation may improve Alzheimer's disease (AD) by correcting metabolic abnormalities, and attenuating inflammation and oxidative stress. This study aimed to determine the effects of probiotic...
A minimal set of physiomarkers in continuous high frequency data streams predict adult sepsis onset earlier.
International journal of medical informatics
Dec 10, 2018
PURPOSE: Sepsis is a life-threatening condition with high mortality rates and expensive treatment costs. To improve short- and long-term outcomes, it is critical to detect at-risk sepsis patients at an early stage.
Validation of Prediction Models for Critical Care Outcomes Using Natural Language Processing of Electronic Health Record Data.
JAMA network open
Dec 7, 2018
IMPORTANCE: Accurate prediction of outcomes among patients in intensive care units (ICUs) is important for clinical research and monitoring care quality. Most existing prediction models do not take full advantage of the electronic health record, usin...
Association Between Early Intravenous Fluids Provided by Paramedics and Subsequent In-Hospital Mortality Among Patients With Sepsis.
JAMA network open
Dec 7, 2018
IMPORTANCE: Early administration of intravenous fluids is recommended for all patients with sepsis, but the association of this treatment with mortality may depend on the patient's initial blood pressure.
Correlation-Aware Sparse and Low-Rank Constrained Multi-Task Learning for Longitudinal Analysis of Alzheimer's Disease.
IEEE journal of biomedical and health informatics
Dec 6, 2018
Alzheimer's disease (AD), as a severe neurodegenerative disease, is now attracting more and more researchers' attention in the healthcare. With the development of magnetic resonance imaging (MRI), the neuroimaging-based longitudinal analysis is gradu...
Vertebral body insufficiency fractures: detection of vertebrae at risk on standard CT images using texture analysis and machine learning.
European radiology
Dec 5, 2018
PURPOSE: To evaluate the diagnostic performance of bone texture analysis (TA) combined with machine learning (ML) algorithms in standard CT scans to identify patients with vertebrae at risk for insufficiency fractures.
Disease Trajectories and End-of-Life Care for Dementias: Latent Topic Modeling and Trend Analysis Using Clinical Notes.
AMIA ... Annual Symposium proceedings. AMIA Symposium
Dec 5, 2018
Despite the increasing prevalence, growing costs, and high mortality of dementia in older adults in the U.S., little is known about the course of these diseases and what care dementia patients receive in their final years of life. Using a large volum...
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