AIMC Topic: Aged, 80 and over

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Assessing brain involvement in Fabry disease with deep learning and the brain-age paradigm.

Human brain mapping
While neurological manifestations are core features of Fabry disease (FD), quantitative neuroimaging biomarkers allowing to measure brain involvement are lacking. We used deep learning and the brain-age paradigm to assess whether FD patients' brains ...

[CLINICAL EVALUATION OF THERAPEUTIC EFFECT PREDICTORS IN PEMBROLIZUMAB FOR ADVANCED UROTHELIAL CANCER].

Nihon Hinyokika Gakkai zasshi. The japanese journal of urology
(Purpose) We performed a clinical retrospective study on the evaluation of pembrolizumab treatment results for advanced urothelial cancer in our hospital. (Materials and Methods) Twenty-seven patients diagnosed with advanced or metastatic urothelial ...

Deep Learning-based U-Mamba Model to Predict Differentiated Gastric Cancer using Radiomics Features from Spleen Segmentation.

Current medical imaging
OBJECTIVE: This study aimed to develop an automated method for segmenting spleen computed tomography (CT) images using a deep learning model to address the limitations of manual segmentation, which is known to be susceptible to inter-observer variabi...

Prediction of Vancomycin-Associated Nephrotoxicity Based on the Area under the Concentration-Time Curve of Vancomycin: A Machine Learning Analysis.

Biological & pharmaceutical bulletin
Several machine learning models have been proposed to predict vancomycin (VCM)-associated nephrotoxicity; however, they have notable limitations. Specifically, they do not use the area under the concentration-time curve (AUC) as recommended in the la...

An Artificial Intelligence-assisted Diagnostic System Improves Upper Urine Tract Cytology Diagnosis.

In vivo (Athens, Greece)
BACKGROUND/AIM: To evaluate efficacy of the AIxURO system, a deep learning-based artificial intelligence (AI) tool, in enhancing the accuracy and reliability of urine cytology for diagnosing upper urinary tract cancers.

Importance of Serum Albumin in Deep Learning-Based Prediction of Cognitive Function Data in the Aged Using a Basic Blood Test.

Advances in experimental medicine and biology
BACKGROUND: Recently, a method using deep learning has been developed to estimate the risk of developing dementia. This method uses general blood test data from routine health examinations that reveal lifestyle-related diseases, which can lead to vas...

A Study of Assisted Screening for Alzheimer's Disease Based on Handwriting and Gait Analysis.

Journal of Alzheimer's disease : JAD
BACKGROUND: Alzheimer's disease (AD) is a progressive neurodegenerative disease that is not easily detected in the early stage. Handwriting and walking have been shown to be potential indicators of cognitive decline and are often affected by AD.

Identification of Dementia & Mild Cognitive Impairment in Chinese Elderly Using Machine Learning.

American journal of Alzheimer's disease and other dementias
OBJECTIVE: To assess the role of Machine Learning (ML) in identification critical factors of dementia and mild cognitive impairment.

Classifying Alzheimer's Disease Neuropathology Using Clinical and MRI Measurements.

Journal of Alzheimer's disease : JAD
BACKGROUND: Computer-aided machine learning models are being actively developed with clinically available biomarkers to diagnose Alzheimer's disease (AD) in living persons. Despite considerable work with cross-sectional in vivo data, many models lack...

Updated Models of Alzheimer's Disease with Deep Neural Networks.

Journal of Alzheimer's disease : JAD
BACKGROUND: In recent years, researchers have focused on developing precise models for the progression of Alzheimer's disease (AD) using deep neural networks. Forecasting the progression of AD through the analysis of time series data represents a pro...