AIMC Topic: Aged

Clear Filters Showing 1191 to 1200 of 14227 articles

Gut microbiome alterations and hepatic encephalopathy post-TIPS in liver cirrhosis patients.

Journal of translational medicine
BACKGROUND: The transjugular intrahepatic portosystemic shunt (TIPS), a crucial tool for treating complications related to portal hypertension in patients with liver cirrhosis, is often associated with an increased risk of postoperative complications...

Prediction of three-year all-cause mortality in patients with heart failure and atrial fibrillation using the CatBoost model.

BMC cardiovascular disorders
BACKGROUND: Heart failure and atrial fibrillation (HF-AF) frequently coexist, resulting in complex interactions that substantially elevate mortality risk. This study aimed to develop and validate a machine learning (ML) model predicting the 3-year al...

Multi-modality radiomics diagnosis of breast cancer based on MRI, ultrasound and mammography.

BMC medical imaging
OBJECTIVE: To develop a multi-modality machine learning-based radiomics model utilizing Magnetic Resonance Imaging (MRI), Ultrasound (US), and Mammography (MMG) for the differentiation of benign and malignant breast nodules.

A robust machine learning approach to predicting remission and stratifying risk in rheumatoid arthritis patients treated with bDMARDs.

Scientific reports
Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting millions worldwide, leading to inflammation, joint damage, and reduced quality of life. Although biological disease-modifying antirheumatic drugs (bDMARDs) are effective, they are co...

Leveraging pathological markers of lower grade glioma to predict the occurrence of secondary epilepsy, a retrospective study.

Scientific reports
Epilepsy is a common manifestation in patients with lower grade glioma (LGG), often presenting as the initial symptom in approximately 70% of cases. This study aimed to identify clinical and pathological markers for epileptic seizures in patients wit...

5-Hydroxymethylcytosine signatures as diagnostic biomarkers for septic cardiomyopathy.

Scientific reports
At present, there are currently no molecular biomarkers for the early diagnosis of sepsis cardiomyopathy (SCM) in clinical practice. This study focuses on an in-depth examination of the DNA hydroxymethylation profiles within plasma extracellular vesi...

Assessment of established prognostic factors and artificial intelligence-based evaluation of tumor-infiltrating lymphocytes in oral tongue squamous cell carcinoma.

Oral oncology
BACKGROUND: Traditional risk assessment for tongue cancer relies on clinicopathological parameters. Although tumor-infiltrating lymphocytes (TILs) are promising prognostic markers, their evaluation lacks standardization. This study aimed to validate ...

Glycoproteomics Analysis to Identify Potential Biomarkers and Investigate CD14 Monocyte Activation Mechanisms via Exosomal Proteins in Cerebral Infarction Using a Novel Glycogen-Functionalized Nanoprobe.

Analytical chemistry
Cerebral infarction (CI) is a leading cause of disability and mortality, with activated plasma monocytes and altered protein glycosylation identified as critical contributors to its pathology. However, the mechanisms linking peripheral monocyte activ...

The value of triglyceride-glucose index-related indices in evaluating migraine: perspectives from multi-centre cross-sectional studies and machine learning models.

Lipids in health and disease
BACKGROUND: This study employed representative data from the U.S. and China to delve into the correlation among migraine prevalence, the triglyceride‒glucose index, a marker of insulin resistance, and the composite indicator of obesity.

Development and external validation of machine learning models for the early prediction of malnutrition in critically ill patients: a prospective observational study.

BMC medical informatics and decision making
BACKGROUND: Early detection of malnutrition in critically ill patients is crucial for timely intervention and improved clinical outcomes. However, identifying individuals at risk remains challenging due to the complexity and variability of patient co...