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Breast cancer is detectable from peripheral blood using machine learning over T cell receptor repertoires.
NPJ systems biology and applications
Aug 8, 2025
The immune system's defense abilities rely on the diversity of T and B lymphocytes. T Cell Receptors (TCRs) are generated through V(D)J recombination, where distinct genetic elements combine and undergo modifications, creating extensive variability. ...
MRI-based radiomics for preoperative T-staging of rectal cancer: a retrospective analysis.
International journal of colorectal disease
Aug 8, 2025
PUROPOSE: Preoperative T-staging in rectal cancer is essential for treatment planning, yet conventional MRI shows limited accuracy (~ 60-78). Our study investigates whether radiomic analysis of high-resolution T2-weighted MRI can non-invasively impro...
Human multiethnic radiogenomics reveals low-abundancy microRNA signature in plasma-derived extracellular vesicles for early diagnosis and molecular subtyping of pancreatic cancer.
eLife
Aug 8, 2025
Pancreatic cancer (PC) is a highly aggressive malignancy in humans, where early diagnosis significantly improves patient outcomes. However, effective methods for accurate and early detection remain limited. In this multiethnic study involving human s...
The analysis of interactive furniture design system based on artificial intelligence.
Scientific reports
Aug 7, 2025
To enhance user interaction experience in furniture customization, this study optimizes an Internet of Things (IoT)-driven Artificial Intelligence (AI)-assisted design system. First, the study analyzes human-computer interaction theories in IoT envir...
Longitudinal structural MRI-based deep learning and radiomics features for predicting Alzheimer's disease progression.
Alzheimer's research & therapy
Aug 7, 2025
BACKGROUND: Alzheimer's disease (AD) is the principal cause of dementia and requires the early diagnosis of people with mild cognitive impairment (MCI) who are at high risk of progressing. Early diagnosis is imperative for optimizing clinical managem...
Machine learning based classification of catastrophic health expenditures: a cross-sectional study of Korean low-income households.
BMC health services research
Aug 7, 2025
BACKGROUND: Despite the National Health Insurance (NHI) system implemented in South Korea, concerns persist regarding access to health coverage for low-income households. To address this issue, this study aims to use machine learning-based data minin...
Remote clinical decision support tool for Parkinson's disease assessment using a novel approach that combines AI and clinical knowledge.
BMC medical informatics and decision making
Aug 7, 2025
BACKGROUND: Early diagnosis of Parkinson's disease (PD) can assist in designing efficient treatments. Reduced facial expressions are considered a hallmark of PD, making advanced artificial intelligence (AI) image processing a potential non-invasive c...
Urinary Complement proteome strongly linked to diabetic kidney disease progression.
Nature communications
Aug 7, 2025
Diabetic kidney disease (DKD) progression is not well understood. Using high-throughput proteomics, biostatistical, pathway and machine learning tools, we examine the urinary Complement proteome in two prospective cohorts with type 1 or 2 diabetes an...
Quantitative image analysis of the extracellular matrix of esophageal squamous cell carcinoma and high grade dysplasia via two-photon microscopy.
Scientific reports
Aug 7, 2025
Squamous cell carcinoma (SCC) and high-grade dysplasia (HGD) are two different pathological entities; however, they sometimes share similarities in histological structure depending on the context. Thus, distinguishing between the two may require care...
Phenotype augmentation using generative AI for isocitrate dehydrogenase mutation prediction in glioma.
Scientific reports
Aug 7, 2025
This study investigated the effects of feature augmentation, which uses generated images with specific imaging features, on the performance of isocitrate dehydrogenase (IDH) mutation prediction models in gliomas. A total of 598 patients were included...
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