With a clinical trial failure rate of 99.6% for Alzheimer's Disease (AD), early diagnosis is critical. Machine learning (ML) models have shown promising results in early AD prediction, with survival ML models outperforming typical classifiers by prov...
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Dec 12, 2024
OBJECTIVE: Alzheimer's disease (AD) and frontotemporal dementia (FTD) are prevalent neurodegenerative diseases characterized by altered brain functional connectivity (FC), affecting over 100 million people worldwide. This study aims to identify disti...
BACKGROUND: This study aimed to develop and apply a novel computational pipeline combining SELFormer, a transformer architecture-based chemical language model, with advanced deep learning techniques to predict natural compounds (NCs) with potential i...
This study investigates the effectiveness of amplitude transformation in enhancing the performance and robustness of Multiscale Fuzzy Entropy for Alzheimer's disease detection using electroencephalography signals. Multiscale Fuzzy Entropy is a comple...
AD is a progressive neurodegenerative disorder characterized by memory loss. Due to the advancement in next-generation sequencing, an enormous amount of AD-associated genomics data is available. However, the information about the involvement of these...
Recently, Deep Learning (DL) models have shown promising accuracy in analysis of medical images. Alzeheimer Disease (AD), a prevalent form of dementia, uses Magnetic Resonance Imaging (MRI) scans, which is then analysed via DL models. To address the ...
The early detection of Alzheimer's Disease (AD) is thought to be important for effective intervention and management. Here, we explore deep learning methods for the early detection of AD. We consider both genetic risk factors and functional magnetic ...
Alzheimer's disease (AD) profoundly affects brain tissue and network structures. Analyzing the topological properties of these networks helps to understand the progression of the disease. Most studies focus on single-scale brain networks, but few add...
Portable, low-field magnetic resonance imaging (LF-MRI) of the brain may facilitate point-of-care assessment of patients with Alzheimer's disease (AD) in settings where conventional MRI cannot. However, image quality is limited by a lower signal-to-n...
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