AIMC Topic: Animals

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Genome-Wide Detection and Analysis of Multifunctional Genes.

PLoS computational biology
Many genes can play a role in multiple biological processes or molecular functions. Identifying multifunctional genes at the genome-wide level and studying their properties can shed light upon the complexity of molecular events that underpin cellular...

Hydrophilic Ionic Liquids as Ingredients of Gel-Based Dermal Formulations.

AAPS PharmSciTech
Ionic liquids (ILs) have several properties that offer many advantages in dermal drug delivery systems. Depending on the chemical structure, ILs can be used for protection against microorganisms, to enhance skin penetration, and as a solvent. In the ...

The Effects of Fluidic Loading on Underwater Contact Sensing with Robotic Fins and Beams.

IEEE transactions on haptics
As robots become more involved in underwater operations, understanding underwater contact sensing with compliant systems is fundamental to engineering useful haptic interfaces and vehicles. Despite knowledge of contact sensation in air, little is kno...

Illuminating the dark matter in metabolomics.

Proceedings of the National Academy of Sciences of the United States of America

Gradual Reduction in Sodium Content in Cooked Ham, with Corresponding Change in Sensorial Properties Measured by Sensory Evaluation and a Multimodal Machine Vision System.

PloS one
The European diet today generally contains too much sodium (Na(+)). A partial substitution of NaCl by KCl has shown to be a promising method for reducing sodium content. The aim of this work was to investigate the sensorial changes of cooked ham with...

Accurate pan-specific prediction of peptide-MHC class II binding affinity with improved binding core identification.

Immunogenetics
A key event in the generation of a cellular response against malicious organisms through the endocytic pathway is binding of peptidic antigens by major histocompatibility complex class II (MHC class II) molecules. The bound peptide is then presented ...

Predicting Mouse Liver Microsomal Stability with "Pruned" Machine Learning Models and Public Data.

Pharmaceutical research
PURPOSE: Mouse efficacy studies are a critical hurdle to advance translational research of potential therapeutic compounds for many diseases. Although mouse liver microsomal (MLM) stability studies are not a perfect surrogate for in vivo studies of m...

Behavior modulation of rats to a robotic rat in multi-rat interaction.

Bioinspiration & biomimetics
In this paper, we study the behavioral response of rats to a robotic rat during multi-rat interaction. Experiments are conducted in an open-field where a robotic rat called WR-5 is put together with three laboratory rats. WR-5 is following one rat (t...

Modelling cephalopod-inspired pulsed-jet locomotion for underwater soft robots.

Bioinspiration & biomimetics
Cephalopods (i.e., octopuses and squids) are being looked upon as a source of inspiration for the development of unmanned underwater vehicles. One kind of cephalopod-inspired soft-bodied vehicle developed by the authors entails a hollow, elastic shel...

IAS: Interaction Specific GO Term Associations for Predicting Protein-Protein Interaction Networks.

IEEE/ACM transactions on computational biology and bioinformatics
Proteins carry out their function in a cell through interactions with other proteins. A large scale protein-protein interaction (PPI) network of an organism provides static yet an essential structure of interactions, which is valuable clue for unders...