Collagen peptides are ubiquitously applied in food systems for their versatile bioactivities but face constraints from labor-intensive enzymatic screening and zoonotic risks from terrestrial sources. This study developed machine learning (ML) models ...
Accurate identification of Vibrio harveyi clade species is critical for seafood safety and the control of aquaculture diseases. However, existing methods demonstrate limited classification performance. This study presents an artificial intelligence-a...
Environmental-friendly fluorocarbon insulating gases have emerged as the preferred substitutes for SF due to their low global warming potential (GWP) and excellent insulation properties. However, current gases face challenges in meeting multiple perf...
BACKGROUND: Minimally invasive microscopic and endoscopic neurosurgery demands precise use of high-speed micro-drilling tools to prevent potential complications. Present-day neuro-drilling training methods include cadaveric specimens and surgical sim...
Lactate dehydrogenase A (LDHA) is a promising target for cancer therapy due to its crucial role in aerobic glycolysis. Despite extensive efforts, the structural diversity of LDHA inhibitors remains limited. Here, we utilized machine learning techniqu...
Confined spaces in the human body pose substantial challenges for biomedical procedures. Navigating these ultrasmall environments is essential for precise drug delivery, improving treatment outcomes and reducing adverse effects. Microrobots offer a p...
Hepatocellular carcinoma (HCC) progression and prognosis are influenced by various molecular markers. This study aimed to identify the hub gene associated with HCC clinical characteristics and its role in HCC progression. Differentially expressed gen...
Crude cone snail venom is a rich source of bioactive compounds with significant therapeutic potential. In this study, we conducted a comprehensive analysis of 5,985 cone snail peptides across 82 Conus species to identify unique cysteine (Cys) pattern...
OBJECTIVE: Diabetic kidney disease (DKD) is a leading cause of chronic kidney disease, with chronic inflammation driving its progression. This study aimed to identify immune-related diagnostic biomarkers for DKD and explore their association with imm...
OBJECTIVE: Bupropion, a norepinephrine-dopamine reuptake inhibitor, is widely used as an antidepressant and smoking cessation aid. At high doses, it also inhibits pancreatic β-cell ATP-sensitive potassium (KATP) channels, inducing insulin secretion. ...
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