AIMC Topic: Animals

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Single-cell omics: moving towards a new era in ischemic stroke research.

European journal of pharmacology
Ischemic stroke (IS) is a highly complex and heterogeneous disease involving multiple pathophysiological events. A better understanding of the pathophysiology of IS will enhance preventive, diagnostic and therapeutic strategies. Despite significant a...

Vibrational spectroscopy of body fluids combined with machine learning for the early diagnosis of cystic echinococcosis.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Cystic echinococcosis (CE) is a globally prevalent zoonotic parasitic disease. Due to the covert symptoms and the inadequacies of screening technologies, accurate early diagnosis is crucial. This study explores the feasibility of employing body fluid...

Deep learning-driven hyperspectral imaging for real-time monitoring and growth modeling of psychrophilic spoilage bacteria in chilled beef.

International journal of food microbiology
Owing to the unsound cold chain system in China, chilled beef's quality would be affected by psychrophilic bacteria, resulting in quality deterioration and corruption, which leads to food safety problems. In this study, the growth of Pseudomonas and ...

Premolar Ecomorphology in Anthropoid Primates: A Machine Learning Approach.

Journal of morphology
Reconstructing the diets of extinct taxa is essential for understanding their ecologies and evolutionary histories, yet traditional methods and proxies such as molar morphology have limited resolution. The potential of premolar morphology as a dietar...

A Unified Explanation for Drug Repurposing and Pharmacological Pleiotropy Based on Classical and Statistical Thermodynamics.

Pharmacology research & perspectives
Drug repurposing is an authentic, emerging, and growing aspect of drug development when the demand for new therapeutic solutions is high. Many repurposed drugs have been discovered by serendipity or a non-ordered process driven by chance and sharp ob...

Endothelial metabolic zonation in the vascular network: a spatiotemporal blueprint for angiogenesis.

American journal of physiology. Heart and circulatory physiology
Angiogenesis, a cornerstone of vascular development, tissue regeneration, and tumor progression, is critically orchestrated by the metabolic behavior of endothelial cells (EC). Recent discoveries have redefined EC not as metabolically uniform entitie...

Multi-Target Drug Design in Alzheimer's Disease Treatment: Emerging Technologies, Advantages, Challenges, and Limitations.

Pharmacology research & perspectives
Alzheimer's disease (AD) is a complex and multifactorial neurodegenerative disorder, recognized as the most prevalent form of dementia. It is characterized by multiple pathological processes, including amyloid-beta accumulation, neurofibrillary tangl...

Nanofiber-Based Biomimetic Platforms for Chronic Wound Healing: Recent Innovations and Future Directions.

Tissue engineering and regenerative medicine
BACKGROUND: Wound healing remains a significant challenge in healthcare, particularly for complex and chronic wounds where conventional treatments often fail to provide effective solutions. Recent advances in nanofiber technology have opened new aven...

Comprehensive duck DNA fingerprinting based on machine learning for breed identification.

Poultry science
Duck is one of the most widely distributed waterfowl in the world, with more than 6 billion of them farmed annually in the world, and has great economic and ecological value. Amidst mounting global prioritization of duck genetic resource exploration ...

A panting behavior-driven assessment framework for summer ventilation quality optimization in layer houses.

Poultry science
Ventilation quality in summer layer houses is critical for heat stress prevention, production performance, and poultry welfare. Addressing the issue of "qualified environmental parameters but chicken discomfort" caused by traditional methods overlook...