AIMC Topic: Animals

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Using Runs of Homozygosity and Machine Learning to Disentangle Sources of Inbreeding and Infer Self-Fertilization Rates.

Genome biology and evolution
Runs of homozygosity (ROHs) are indicative of elevated homozygosity and inbreeding due to mating of closely related individuals. Self-fertilization can be a major source of inbreeding which elevates genome-wide homozygosity and thus should also creat...

A Pan-Cancer Patient-Derived Xenograft Histology Image Repository with Genomic and Pathologic Annotations Enables Deep Learning Analysis.

Cancer research
Patient-derived xenografts (PDX) model human intra- and intertumoral heterogeneity in the context of the intact tissue of immunocompromised mice. Histologic imaging via hematoxylin and eosin (H&E) staining is routinely performed on PDX samples, which...

Integrating Microfluidics and Deep Learning to Investigate Entomopathogenic Nematode Responses to Host Cues.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Entomopathogenic nematodes (EPNs) are effective biocontrol agents, reducing pesticide impact on health and the environment. Understanding their physiology and ethology is crucial for optimizing their application. This study offers innovative insights...

Minimally invasive monitor of cardiac output based on the machine-learning analysis of the pulse contour of the peripheral arterial pressure.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
In the hemodynamic management of anesthetized patients during surgical operation, minimally invasive and accurate cardiac output (CO) monitoring is strongly required. We have developed a CO monitor based on the machine-learning analysis of the pulse ...

A Robotic Injection System for Consistent Pneumo-dissection of the Deep Stroma in Big Bubble DALK Surgery.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
In this paper we present a novel robotic injection system capable of performing clinically relevant pneumo-dissection of the deep stroma for the big bubble DALK procedure. Because the recommended clinical technique to insert a needle into the deep st...

The Recurrent U-Net for Needle Segmentation in Ultrasound Image-Guided Surgery.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
In minimally invasive surgery, poor needle visualization under ultrasound has been one of the challenges of the surgery. To improve the resulting puncture error, it is effective to use deep learning from the image level to assist the surgeon in locat...

Transformer-Based Wavelet-Scalogram Deep Learning for Improved Seizure Pattern Recognition in Post-Hypoxic-Ischemic Fetal Sheep EEG.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Hypoxic-ischemic (HI) events in newborns can trigger seizures, which are highly associated with later neurodevelopmental impairment. The precise detection of these seizures is a complex task requiring considerable very specialized expertise, undersco...

A CNN-GNN Approach for Polarity Vectors Prediction in 3D Microscopy Images.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
The polarity between nuclei and Golgi is an important aspect of cellular division, migration and signaling. For example, nucleus-Golgi polarity significantly impacts angiogenesis, the physiological process in which new blood vessels develop from pre-...

Spike Neural Network of Motor Cortex Model for Arm Reaching Control.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Motor cortex modeling is crucial for understanding movement planning and execution. While interconnected recurrent neural networks have successfully described the dynamics of neural population activity, most existing methods utilize continuous signal...

Recapitulating the electrophysiological features of in vivo biological networks by using a real-time hardware Spiking Neural Network.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Electroceutical methodologies utilized for treating neurological disorders, including stroke, can leverage neuromorphic engineering principles to design devices capable of seamlessly interfacing with the neural system. This paper introduces a bank of...