AIMC Topic: Animals

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Protective effect of Yiguanjian decoction against DNA damage on concanavalin A-induced liver injury mice model.

Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
OBJECTIVE: To investigate the inhibitory effect of Yiguanjian decoction (YD) on DNA damage in Concanavalin A (Con A)-induced liver injury mice model and to explain the possible mechanism.

Improving odorant chemical class prediction with multi-layer perceptrons using temporal odorant spike responses from drosophila melanogaster olfactory receptor neurons.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
In this work, we examine the possibility of improving the prediction performance of an olfactory biosensor through the use of temporal spiking data. We present an Artificial Neural Network (ANN), in the form of an optimal hybrid Multi-Layer Perceptro...

Multi-chip dataflow architecture for massive scale biophysically accurate neuron simulation.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
State-of-the-art neuron simulators are capable of simulating at most few tens/hundreds of neurons in real-time due to the exponential growth in the communication costs with the number of simulated neurons. In this paper, we present a novel, reconfigu...

Prediction of individual prosthesis size for valve-sparing aortic root reconstruction based on geometric features.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Valve-sparing aortic root reconstruction is an up- and-coming approach for patients suffering from aortic valve insufficiencies which promises to significantly reduce complications. However, the success of the treatment strongly depends on the challe...

Non-invasive optical imaging techniques for burn-injured tissue detection for debridement surgery.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Burn debridement is a challenging technique that requires significant skill to identify regions requiring excision and appropriate excision depth. A machine learning tool is being developed in order to assist surgeons by providing a quantitative asse...

Preliminary statistical assessment towards characterization of biobotic control.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Biobotic research involving neurostimulation of instrumented insects to control their locomotion is finding potential as an alternative solution towards development of centimeter-scale distributed swarm robotics. To improve the reliability of bioboti...

A device for controlled jet injection of large volumes of liquid.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
We present a needle-free jet injection device controllably actuated by a voice coil and capable of injecting up to 1.3 mL. This device is used to perform jet injections of ~900 μL into porcine tissue. This is the first time that delivery of such a la...

Assistive Device for Efficient Intravitreal Injections.

Ophthalmic surgery, lasers & imaging retina
Intravitreal therapy is the most common treatment for many chronic ophthalmic diseases, such as age-related macular degeneration. Due to the increasing worldwide demand for intravitreal injections, there exists a need to render this medical procedure...

A fuzzy logic controller based approach to model the switching mechanism of the mammalian central carbon metabolic pathway in normal and cancer cells.

Molecular bioSystems
Dynamics of large nonlinear complex systems, like metabolic networks, depend on several parameters. A metabolic pathway may switch to another pathway in accordance with the current state of parameters in both normal and cancer cells. Here, most of th...

Phototactic guidance of a tissue-engineered soft-robotic ray.

Science (New York, N.Y.)
Inspired by the relatively simple morphological blueprint provided by batoid fish such as stingrays and skates, we created a biohybrid system that enables an artificial animal--a tissue-engineered ray--to swim and phototactically follow a light cue. ...