AIMC Topic: Antineoplastic Combined Chemotherapy Protocols
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Validation of a Cyclic Algorithm to Proxy Number of Lines of Systemic Cancer Therapy Using Administrative Data.
JCO clinical cancer informatics
Aug 1, 2019
PURPOSE: Researchers are automating the process for identifying the number of lines of systemic cancer therapy received by patients. To date, algorithm development has involved manual modifications to predefined classification rules. In this study, w...
Predicting response to cancer immunotherapy using noninvasive radiomic biomarkers.
Annals of oncology : official journal of the European Society for Medical Oncology
Jun 1, 2019
INTRODUCTION: Immunotherapy is regarded as one of the major breakthroughs in cancer treatment. Despite its success, only a subset of patients responds-urging the quest for predictive biomarkers. We hypothesize that artificial intelligence (AI) algori...
Antineoplastic Combined Chemotherapy Protocols
Carcinoma, Non-Small-Cell Lung
Follow-Up Studies
Predictive Value of Tests
Survival Rate
Lung Neoplasms
Immunotherapy
Humans
Artificial Intelligence
Machine Learning
Programmed Cell Death 1 Receptor
Algorithms
Prognosis
Tomography, X-Ray Computed
Melanoma
[A Case of Laparoscopic Resection for Locally Advanced Primary Rectal Cancer after Neoadjuvant Chemotherapy].
Gan to kagaku ryoho. Cancer & chemotherapy
Dec 1, 2018
We treateda 70-year-oldfemale patient with locally advancedrectal cancer accompaniedby metastases to other organs. Three courses of S-1 plus oxaliplatin(SOX)therapy were administered as neoadjuvant chemotherapy(NAC), andthe cancer was subsequently tr...
[Nephrotoxicity of a Short Hydration Method for the Cisplatin Regimen in Patients with Gastric Cancer].
Gan to kagaku ryoho. Cancer & chemotherapy
Dec 1, 2018
BACKGROUND: S-1 plus cisplatin(CDDP)has been a key regimen for advanced gastric cancer treatment. However, CDDP confers dose-limiting nephrotoxicity, requires a hospital stay for conventional massive hydration, and reduces patients' quality of life. ...
DeepSynergy: predicting anti-cancer drug synergy with Deep Learning.
Bioinformatics (Oxford, England)
May 1, 2018
MOTIVATION: While drug combination therapies are a well-established concept in cancer treatment, identifying novel synergistic combinations is challenging due to the size of combinatorial space. However, computational approaches have emerged as a tim...
[RETROPERITONEAL LIPOSARCOMA WITH MULTIPLE RECURRENCE OF LUNG METASTASES TREATED BY MULTIMODAL THERAPY CENTERING ON THE OPERATION: A CASE REPORT].
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology
Jan 1, 2018
A 34-year-old man presented with scrotal pain and slight fever. The scrotal pain was improved by the treatment of antibiotics, but the slight fever remained and an abdominal protuberance appeared. Computed tomography showed a 22 cm abdominal tumor wi...
Thoracoscopy
Etoposide
Ifosfamide
Humans
Liposarcoma
Adult
Retroperitoneal Neoplasms
Treatment Outcome
Male
Combined Modality Therapy
Time Factors
Doxorubicin
Lung Neoplasms
Lymph Node Excision
Surgical Procedures, Operative
Antineoplastic Combined Chemotherapy Protocols
Pneumonectomy
Neoplasm Recurrence, Local
[Neoadjuvant FOLFIRINOX for Unresectable Adenocarcinoma of the Pancreas - A Case Report].
Gan to kagaku ryoho. Cancer & chemotherapy
Nov 1, 2017
A 38-year-old male presented to our hospital with complaint of vomiting. A CT demonstrated a mass sized 42mm in the pancreatic head invading to the duodenum and a liver mass sized 15mm in the medial segment. Biopsy revealed adenocarcinoma. Due to liv...
[A Case of Advanced Gastric Cancer with Synchronous Liver Metastases Responding to Preoperative Combination Chemotherapy with S-1 plus Oxaliplatin(SOX)].
Gan to kagaku ryoho. Cancer & chemotherapy
Nov 1, 2017
A 67-year-old man was admitted to our hospital because of anemia and weight loss, and diagnosed with a type 3 tumor in the upper gastric body. Pathological examination suggested moderately differentiated adenocarcinoma with immunohistochemically nega...
Development and validation of a LC-FL method for the simultaneous determination of doxorubicin and celecoxib in nanoparticulate fixed dose combination (NanoFDC).
Die Pharmazie
Oct 1, 2017
An isocratic reversed phase HPLC method for the simultaneous determination of doxorubicine (DOX) and celecoxib (CXB) out of a nanoparticulate fixed dose combination (NanoFDC) was developed and validated. Linearity of the results was demonstrated from...
A comparative phase III clinical study to evaluate efficacy and safety of TrastuRel™ (biosimilar trastuzumab) and innovator trastuzumab in patients with metastatic human epidermal growth factor receptor 2 (HER2)-overexpressing breast cancer.
Indian journal of cancer
Jan 1, 2017
INTRODUCTION: The present study for biosimilar trastuzumab was a multicentric, randomized, two-arm parallel-group, comparative phase III study in patients with metastatic breast cancer.
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