AIMC Topic: Area Under Curve

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Drug Repositioning by Integrating Known Disease-Gene and Drug-Target Associations in a Semi-supervised Learning Model.

Acta biotheoretica
Computational drug repositioning has been proven as a promising and efficient strategy for discovering new uses from existing drugs. To achieve this goal, a number of computational methods have been proposed, which are based on different data sources...

Machine learning to predict the occurrence of bisphosphonate-related osteonecrosis of the jaw associated with dental extraction: A preliminary report.

Bone
INTRODUCTION: The aim of this study was to build and validate five types of machine learning models that can predict the occurrence of BRONJ associated with dental extraction in patients taking bisphosphonates for the management of osteoporosis.

Computer-aided diagnosis of lung nodule using gradient tree boosting and Bayesian optimization.

PloS one
We aimed to evaluate a computer-aided diagnosis (CADx) system for lung nodule classification focussing on (i) usefulness of the conventional CADx system (hand-crafted imaging feature + machine learning algorithm), (ii) comparison between support vect...

Using machine learning on cardiorespiratory fitness data for predicting hypertension: The Henry Ford ExercIse Testing (FIT) Project.

PloS one
This study evaluates and compares the performance of different machine learning techniques on predicting the individuals at risk of developing hypertension, and who are likely to benefit most from interventions, using the cardiorespiratory fitness da...

Predicting Changes in Pediatric Medical Complexity using Large Longitudinal Health Records.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Medically complex patients consume a disproportionate amount of care resources in hospitals but still often end up with sub-optimal clinical outcomes. Predicting dynamics of complexity in such patients can potentially help improve the quality of care...

Classifying Acute Ischemic Stroke Onset Time using Deep Imaging Features.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Models have been developed to predict stroke outcomes (e.g., mortality) in attempt to provide better guidance for stroke treatment. However, there is little work in developing classification models for the problem of unknown time-since-stroke (TSS), ...

Calibration Drift Among Regression and Machine Learning Models for Hospital Mortality.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Advanced regression and machine learning models can provide personalized risk predictions to support clinical decision-making. We aimed to understand whether modeling methods impact the tendency of calibration to deteriorate as patient populations sh...

Automated detection of focal cortical dysplasia type II with surface-based magnetic resonance imaging postprocessing and machine learning.

Epilepsia
OBJECTIVE: Focal cortical dysplasia (FCD) is a major pathology in patients undergoing surgical resection to treat pharmacoresistant epilepsy. Magnetic resonance imaging (MRI) postprocessing methods may provide essential help for detection of FCD. In ...

Transfer Learning for Molecular Cancer Classification Using Deep Neural Networks.

IEEE/ACM transactions on computational biology and bioinformatics
The emergence of deep learning has impacted numerous machine learning based applications and research. The reason for its success lies in two main advantages: 1) it provides the ability to learn very complex non-linear relationships between features ...