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The Gene Ontology Resource: 20 years and still GOing strong.

Nucleic acids research
The Gene Ontology resource (GO; http://geneontology.org) provides structured, computable knowledge regarding the functions of genes and gene products. Founded in 1998, GO has become widely adopted in the life sciences, and its contents are under cont...

Learned protein embeddings for machine learning.

Bioinformatics (Oxford, England)
MOTIVATION: Machine-learning models trained on protein sequences and their measured functions can infer biological properties of unseen sequences without requiring an understanding of the underlying physical or biological mechanisms. Such models enab...

Cost function network-based design of protein-protein interactions: predicting changes in binding affinity.

Bioinformatics (Oxford, England)
MOTIVATION: Accurate and economic methods to predict change in protein binding free energy upon mutation are imperative to accelerate the design of proteins for a wide range of applications. Free energy is defined by enthalpic and entropic contributi...

An mRMR-SVM Approach for Opto-Fluidic Microorganism Classification.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
The detection of microorganisms is important in numerous applications such as water quality monitoring, blood analysis, and food testing. The conventional detection methods are tedious and labour-intensive. Establish methods involve culturing, counti...

DeepSig: deep learning improves signal peptide detection in proteins.

Bioinformatics (Oxford, England)
MOTIVATION: The identification of signal peptides in protein sequences is an important step toward protein localization and function characterization.

DeepGO: predicting protein functions from sequence and interactions using a deep ontology-aware classifier.

Bioinformatics (Oxford, England)
MOTIVATION: A large number of protein sequences are becoming available through the application of novel high-throughput sequencing technologies. Experimental functional characterization of these proteins is time-consuming and expensive, and is often ...

Tiny Conveyance: Micro- and Nanorobots Prepare to Advance Medicine.

IEEE pulse
In the science-fiction classic Fantastic Voyage [1], a shrink-ray zaps a submarine and the crew within it, and the resulting microscopic vehicle ventures inside a human body to destroy a blood clot and save a prominent patient's life. While that scen...

[Effects of Soil Microbial Diversity on the Phosphate Fraction in the Rhizosphere of in the Yeyahu Wetland in Beijing, China].

Huan jing ke xue= Huanjing kexue
In this research, microorganisms in rhizosphere/non-rhizosphere soils of in the Yeyahu Wetland were studied. A sequential extraction procedure was used to analyze the phosphorus (P) forms in the rhizosphere/non-rhizosphere soil with a variety of pla...

[Enhanced Treatment of Printing and Dyeing Wastewater Using HO-Biochemical Method].

Huan jing ke xue= Huanjing kexue
The traditional biochemical treatment of printing and dyeing wastewater has limited efficiency. This study investigated whether HO could strengthen the biological ability of the hydrolytic acidification/biological contact oxidation process (A/O), whi...