AIMC Topic: Biosensing Techniques

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Machine learning-assisted detection of single-point mutations DNA-templated gold nanoparticle growth.

Nanoscale
Detecting single point mutations, such as PIK3CA mutations, is vital for precision diagnostics but remains challenging due to subtle sequence differences. This study introduces a machine learning-assisted colorimetric biosensor that utilizes DNA-temp...

From biosensing to perception: Collaborative few-shot learning for explainable digital biomarker identification in high-dimensional biomedical spectra.

Biosensors & bioelectronics
The application of in vitro diagnostic biosensors for early cancer detection remains challenging due to the insufficient representation by a few molecular biomarkers. Digital biomarkers promise comprehensive disease phenotyping but face constraints o...

Rapid Template-Transferred Printing of Gelatin-Based Ionogels with Bioinspired Hierarchical Microstructures for Flexible Tactile Sensors.

Biomacromolecules
Flexible pressure sensors are pivotal for e-skin, artificial intelligence interactions, and personalized medicine. Nevertheless, integrating high sensitivity, a broad detection range, and biodegradability remains difficult. Herein, we developed a fle...

Dual-Chronoamperometry Drift Correction for Electrochemical Sensors.

ACS sensors
Accurate sensing of biomolecular targets is crucial for diagnosing diseases and developing technologies for personalized medicine. However, measuring biomarker levels with high precision is often challenging due to signal drift caused by biofouling a...

Cutting-edge nanobiosensors: Revolutionizing cancer diagnosis and enabling precision medicine.

Clinica chimica acta; international journal of clinical chemistry
Integrating nanotechnology and artificial intelligence (AI) revolutionizes cancer diagnostics, propelling precision medicine into a transformative era. This review examines state-of-the-art nanobiosensors capable of detecting critical biomarkers-circ...

Dynamic forecasting of beef freshness using multi-step time series analysis of electronic nose signals.

Biosensors & bioelectronics
The preservation of microbial quality in meat products represents a fundamental challenge in contemporary food supply chain management due to the highly perishable nature of these commodities. Although modern testing techniques, particularly electron...

A magnetic coupled organic SERS platform integrating acetonitrile-driven microextraction and hotspot enrichment: A new strategy for highly sensitive and precise detection of drug molecules in complex matrices.

Biosensors & bioelectronics
The sensitive detection of drug molecules in complex biological samples presents significant challenges, including weak signal intensity, strong matrix interference, and inefficient access of molecules to SERS hotspots. To address these issues, this ...

Neurochemical profiling in urine: Multiplexed detection of dopamine and serotonin using ML-integrated laser-induced graphene biosensors.

Biosensors & bioelectronics
Simultaneous monitoring of dopamine (DA) and serotonin (SER) in urine offers a non-invasive route for diagnosing neurological, psychiatric, and metabolic disorders. However, their multiplexed detection at the point-of-care remains challenging due to ...

YOLOv5-aided paper-based microfluidic intelligent sensing platform for multiplex sweat biomarker analysis.

Biosensors & bioelectronics
Sweat, a biofluid rich in various biomarkers, offers significant potential for non-invasive health monitoring and disease screening. Colorimetric detection is well-suited for multi-analyte quantification and point-of-care testing in sweat analysis, w...

Wearable Point-of-Care Biosensor for Biomolecular Assay in Health Monitoring.

ACS applied bio materials
Wearable biosensors represent a significant advancement in preventive health monitoring by enabling early disease detection through real-time bioanalysis. This review examines the evolution of point-of-care testing (POCT), with a focus on materials, ...