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Brain Neoplasms

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Multiparametric MRI along with machine learning predicts prognosis and treatment response in pediatric low-grade glioma.

Nature communications
Pediatric low-grade gliomas (pLGGs) exhibit heterogeneous prognoses and variable responses to treatment, leading to tumor progression and adverse outcomes in cases where complete resection is unachievable. Early prediction of treatment responsiveness...

Cooperative multi-task learning and interpretable image biomarkers for glioma grading and molecular subtyping.

Medical image analysis
Deep learning methods have been widely used for various glioma predictions. However, they are usually task-specific, segmentation-dependent and lack of interpretable biomarkers. How to accurately predict the glioma histological grade and molecular su...

Predicting local control of brain metastases after stereotactic radiotherapy with clinical, radiomics and deep learning features.

Radiation oncology (London, England)
BACKGROUND AND PURPOSE: Timely identification of local failure after stereotactic radiotherapy for brain metastases allows for treatment modifications, potentially improving outcomes. While previous studies showed that adding radiomics or Deep Learni...

Advancing brain tumor detection and classification in Low-Dose CT images using the innovative multi-layered deep neural network model.

Technology and health care : official journal of the European Society for Engineering and Medicine
BackgroundEffective brain tumour therapy and better patient outcomes depend on early tumour diagnosis. Accurate diagnosis can be hampered by traditional imaging techniques' frequent struggles with low resolution and noise, especially in Low Dose CT s...

Differentiation of glioblastoma G4 and two types of meningiomas using FTIR spectra and machine learning.

Analytical biochemistry
Brain tumors are among the most dangerous, due to their location in the organ that governs all life processes. Moreover, the high differentiation of these poses a challenge in diagnostics. Therefore, this study focused on the chemical differentiation...

Survival prediction of glioblastoma patients using machine learning and deep learning: a systematic review.

BMC cancer
Glioblastoma Multiforme (GBM), classified as a grade IV glioma by the World Health Organization (WHO), is a prevalent and notably aggressive form of brain tumor derived from glial cells. It stands as one of the most severe forms of primary brain canc...

MRI-derived radiomics and end-to-end deep learning models for predicting glioma ATRX status: a systematic review and meta-analysis of diagnostic test accuracy studies.

Clinical imaging
We aimed to systematically review and meta-analyze the predictive value of magnetic resonance imaging (MRI)-derived radiomics/end-to-end deep learning (DL) models in predicting glioma alpha thalassemia/mental retardation syndrome X-linked (ATRX) stat...

Brain multi modality image inpainting via deep learning based edge region generative adversarial network.

Technology and health care : official journal of the European Society for Engineering and Medicine
A brain tumor (BT) is considered one of the most crucial and deadly diseases in the world, as it affects the central nervous system and its main functions. Headaches, nausea, and balance problems are caused by tumors pressing on nearby brain tissue a...

Radiomics and deep learning models for glioblastoma treatment outcome prediction based on tumor invasion modeling.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: We investigate the feasibility of using a biophysically guided approach for delineating the Clinical Target Volume (CTV) in Glioblastoma Multiforme (GBM) by evaluating its impact on the treatment outcomes, specifically Overall Survival (OS) ...

Ensemble learning-based radiomics model for discriminating brain metastasis from glioblastoma.

European journal of radiology
OBJECTIVE: Differentiating between brain metastasis (BM) and glioblastoma (GBM) preoperatively is challenging due to their similar imaging features on conventional brain MRI. This study aimed to enhance diagnostic accuracy through a machine learning ...