AIMC Topic: Brain

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Machine learning model for predicting Amyloid-β positivity and cognitive status using early-phase F-Florbetaben PET and clinical features.

Scientific reports
This study developed machine learning models to predict Aβ positivity in Alzheimer's disease by integrating early-phase F-Florbetaben PET and clinical data to improve diagnostic accuracy. Furthermore, the study explored machine learning models to pre...

Ultradeep N-glycoproteome atlas of mouse reveals spatiotemporal signatures of brain aging and neurodegenerative diseases.

Nature communications
The current depth of site-specific N-glycoproteomics is insufficient to fully characterize glycosylation events in biological samples. Herein, we achieve an ultradeep and precision analysis of the N-glycoproteome of mouse tissues by integrating multi...

Brain-wide input-output analysis of tuberal nucleus somatostatin neurons reveals hierarchical circuits for orchestrating feeding behavior.

Nature communications
Feeding is an innate behavior critical for survival but is also influenced by many non-nutritional factors such as emotion, social context and environmental conditions. Recently, tuberal nucleus somatostatin (SST) neurons have been identified as a ke...

Artificial intelligence meets brain theory (again).

Biological cybernetics
After noting the cybernetic origins of Kybernetik/ Biological Cybernetics, we respond to the Editorial by Fellous et al. (2025) and then analyze talks from the NIH BRAIN NeuroAI 2024 Workshop to get one "snapshot" of the state of the conversation bet...

Neurons throughout the brain embed robust signatures of their anatomical location into spike trains.

eLife
Neurons in the brain are known to encode diverse information through their spiking activity, primarily reflecting external stimuli and internal states. However, whether individual neurons also embed information about their own anatomical location wit...

Speech imagery brain-computer interfaces: a systematic literature review.

Journal of neural engineering
Speech Imagery (SI) refers to the mental experience of hearing speech and may be the core of verbal thinking for people who undergo internal monologues. It belongs to the set of possible mental imagery states that produce kinesthetic experiences whos...

BrainNet-GAN: Generative Adversarial Graph Convolutional Network for Functional Brain Network Synthesis from Routine Clinical Brain Structural T1-Weighted Sequence.

Brain topography
Functional brain network (FBN) derived from functional Magnetic Resonance Imaging (fMRI) has promising prospects in clinical research, but fMRI is not a routine acquisition data, which limits its popularity in clinical applications. Therefore, it is ...

Role of Brain Age Gap as a Mediator in the Relationship Between Cognitive Impairment Risk Factors and Cognition.

Neurology
BACKGROUND AND OBJECTIVES: Cerebrovascular disease (CeVD) and cognitive impairment risk factors contribute to cognitive decline, but the role of brain age gap (BAG) in mediating this relationship remains unclear, especially in Southeast Asian populat...

Identifying and predicting EEG microstates with sequence-to-sequence deep learning models for online applications.

Journal of neural engineering
Electroencephalographic (EEG) microstates, as a non-invasive and high-temporal-resolution tool for analyzing time-space features of brain activity, have been validated and applied in various research domains. However, current methods for EEG microsta...

Rate of brain aging associates with future executive function in Asian children and older adults.

eLife
Brain age has emerged as a powerful tool to understand neuroanatomical aging and its link to health outcomes like cognition. However, there remains a lack of studies investigating the rate of brain aging and its relationship to cognition. Furthermore...