Early diagnosis of Alzheimer's disease (AD) and its precursor, mild cognitive impairment (MCI), is critical for effective prevention and treatment. Computer-aided diagnosis using magnetic resonance imaging (MRI) provides a cost-effective and objectiv...
Proceedings of the National Academy of Sciences of the United States of America
Jul 30, 2025
Past traumatic experiences shape neural responses to future stress, but the mechanisms underlying this dynamic interaction remain unclear. Here, we assessed how trauma-related brain networks respond to current acute stress in real time. Using a machi...
BACKGROUND: Visual cognitive impairment is among the most common postoperative cognitive dysfunctions, significantly impacting recovery and quality of life in elderly patients. However, effective preoperative prediction methods remain lacking. We dev...
Brain networks exhibit diverse topological structures to adapt and support brain functions. The changes in neuronal network architecture can lead to alterations in neuronal spiking activity, yet how individual neuronal behavior reflects network struc...
Alzheimer's disease is a progressive neurological disorder that profoundly affects cognitive functions and daily activities. Rapid and precise identification is essential for effective intervention and improved patient outcomes. This research introdu...
BACKGROUND: Autonomous sensory meridian response (ASMR) videos have been increasingly popularized as accessible tools for stress relief. Despite widespread media coverage promoting their benefits, empirical research on the neural mechanisms underlyin...
Deep learning techniques have become pivotal in medical image segmentation, but their success often relies on large, manually annotated datasets, which are expensive and labor-intensive to obtain. Additionally, different segmentation tasks frequently...
. Nearly one-third of stroke patients develop aphasia. Although the function of classical language areas (e.g. Broca's area, Wernicke's area) has been widely characterized, the network reorganization mechanisms behind specific language dysfunctions i...
Prolonged disorders of consciousness (pDoC) in children lack objective and effective diagnostic methods to assess consciousness states, hindering targeted treatment selection and delaying recovery. It remains unclear whether EEG microstate analysis, ...
Sparse-view computed tomography (CT) holds promise for reducing radiation exposure and enabling novel system designs. Traditional reconstruction algorithms, including Filtered Backprojection (FBP) and Model-Based Iterative Reconstruction (MBIR), ofte...
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