AIMC Topic: Cell Proliferation
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Morphology-based deep learning enables accurate detection of senescence in mesenchymal stem cell cultures.
BMC biology
Jan 2, 2024
BACKGROUND: Cell senescence is a sign of aging and plays a significant role in the pathogenesis of age-related disorders. For cell therapy, senescence may compromise the quality and efficacy of cells, posing potential safety risks. Mesenchymal stem c...
Effects of targeting highly expressed in cancer protein 1 (Hec1) inhibitor INH 1 in breast cancer cell lines In Vitro.
Cellular and molecular biology (Noisy-le-Grand, France)
Dec 20, 2023
In the present study, the in vitro antiproliferative effect of targeting highly expressed cancer protein 1 (Hec1) inhibitor INH1 was investigated in estrogen receptor-positive MCF-7 cell line originating from an in situ carcinoma and triple negative ...
The effect of thalidomide on the invasive ability of gastric cancer cells by regulating miR-524-5p/FSTL1.
Cellular and molecular biology (Noisy-le-Grand, France)
Dec 20, 2023
This study aimed to investigate the effect of thalidomide (Thal) regulating microRNA (miR)-524-5p/follistatin-like protein 1 (FSTL1) on the invasion ability of gastric cancer cells. For this purpose, real-time fluorescent quantitative PCR (RT-qPCR) w...
Machine learning and experimental screening of chromatin regulator signatures and potential drugs in hepatitis B related hepatocellular carcinoma.
Journal of biomolecular structure & dynamics
Dec 18, 2023
Many evidences have confirmed that chromatin regulator factors (CRs) are involved in the progression of cancer, but its potential mechanism of affecting hepatitis B related hepatocellular carcinoma still needs to be studied. Our study detected the CR...
Identifying multi-target drugs for prostate cancer using machine learning-assisted transcriptomic analysis.
Journal of biomolecular structure & dynamics
Dec 16, 2023
Prostate cancer is a leading cause of cancer death in men, and the development of effective treatments is of great importance. This study explored to identify the candidate drugs for prostate cancer by transcriptomic data and CMap database analysis. ...
Smart Sensor Control and Monitoring of an Automated Cell Expansion Process.
Sensors (Basel, Switzerland)
Dec 7, 2023
Immune therapy for cancer patients is a new and promising area that in the future may complement traditional chemotherapy. The cell expansion phase is a critical part of the process chain to produce a large number of high-quality, genetically modifie...
Ki67 proliferation index in medullary thyroid carcinoma: a comparative study of multiple counting methods and validation of image analysis and deep learning platforms.
Histopathology
Sep 14, 2023
AIMS: The International Medullary Thyroid Carcinoma Grading System, introduced in 2022, mandates evaluation of the Ki67 proliferation index to assign a histological grade for medullary thyroid carcinoma. However, manual counting remains a tedious and...
Machine learning and biological evaluation-based identification of a potential MMP-9 inhibitor, effective against ovarian cancer cells SKOV3.
Journal of biomolecular structure & dynamics
Jul 28, 2023
MMP-9, also known as gelatinase B, is a zinc-metalloproteinase family protein that plays a key role in the degradation of the extracellular matrix (ECM). The normal function of MMP-9 includes the breakdown of ECM, a process that aids in normal physio...
A review on proliferation of artificial intelligence in wind energy forecasting and instrumentation management.
Environmental science and pollution research international
Apr 18, 2022
Energy is the source of economic growth, and energy consumption indicates the country's state of development. Energy engineering is a relatively new technical discipline. It is increasingly considered as a significant step in meeting carbon reduction...
Exploring the Study of miR-1301 Inhibiting the Proliferation and Migration of Squamous Cell Carcinoma YD-38 Cells through PI3K/AKT Pathway under Deep Learning Medical Images.
Computational intelligence and neuroscience
Feb 10, 2022
With the rapid development and application of deep learning medical image recognition, natural language processing, and other fields, at the same time, deep learning has become the most popular research direction in the field of image processing and ...
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