Worldwide, there are nearly 10 million new cases of dementia annually, of which Alzheimer's disease (AD) is the most common. New measures are needed to improve the diagnosis of individuals with cognitive impairment due to various etiologies. Here, we...
Alzheimer's & dementia : the journal of the Alzheimer's Association
Jun 6, 2022
INTRODUCTION: To test the utility of the "A/T/N" system in the Chinese population, we study core Alzheimer's disease (AD) biomarkers in a newly established Chinese cohort.
OBJECTIVES: Neuropsychological tests (NPTs) are widely used tools to evaluate cognitive functioning. The interpretation of these tests can be time-consuming and requires a specialized clinician. For this reason, we trained machine learning models tha...
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Jun 2, 2022
PURPOSE: To validate our previously proposed method of quantifying amyloid-beta (Aβ) load using nonspecific (NS) estimates generated with convolutional neural networks (CNNs) using [F]Florbetapir scans from longitudinal and multicenter ADNI data.
Disability and rehabilitation. Assistive technology
May 19, 2022
BACKGROUND: Due to increasing age and an increasing prevalence rate of neurocognitive disorders such as Mild Cognitive Impairment (MCI) and dementia, independent living may become challenging. The use of socially assistive robots (SARs) is one soluti...
BACKGROUND: The improvement of health indicators and life expectancy, especially in developed countries, has led to population growth and increased age-related diseases, including Alzheimer's disease (AD). Thus, the early detection of AD is valuable ...
IEEE journal of biomedical and health informatics
Apr 14, 2022
Machine learning (ML) algorithms play a vital role in the brain age estimation frameworks. The impact of regression algorithms on prediction accuracy in the brain age estimation frameworks have not been comprehensively evaluated. Here, we sought to a...
Early and accurate diagnosis of Alzheimer's disease (AD) and its prodromal period mild cognitive impairment (MCI) is essential for the delayed disease progression and the improved quality of patients' life. The emerging computer-aided diagnostic meth...
Research on segmentation of the hippocampus in magnetic resonance images through deep learning convolutional neural networks (CNNs) shows promising results, suggesting that these methods can identify small structural abnormalities of the hippocampus,...
The study aimed to explore the risk factors of effects of patients with vascular mild cognitive impairment (VaMCI) through functional magnetic resonance imaging (fMRI). In this study, 62 patients were selected from the department of neurology, admitt...