AIMC Topic: Cohort Studies

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Serum phosphate as an additional marker for initiating hemodialysis in patients with advanced chronic kidney disease.

Biomedical journal
BACKGROUND: Reconsidering when to initiate renal replacement therapy (RRT) in patients with chronic kidney disease (CKD) has been emphasized recently. With evolving modern aged and diabetes-prone populations, conventional markers of uremia are not su...

Cognitively impaired elderly exhibit insulin resistance and no memory improvement with infused insulin.

Neurobiology of aging
Insulin resistance is a risk factor for Alzheimer's disease (AD), although its role in AD etiology is unclear. We assessed insulin resistance using fasting and insulin-stimulated measures in 51 elderly subjects with no dementia (ND; n = 37) and with ...

Vitamin D status in youth with type 1 and type 2 diabetes enrolled in the Pediatric Diabetes Consortium (PDC) is not worse than in youth without diabetes.

Pediatric diabetes
OBJECTIVE: To describe vitamin D levels and prevalence of vitamin D sufficiency, insufficiency and deficiency in a large, ethnically/racially diverse population of youth with type 1 diabetes (T1D) and type 2 diabetes (T2D) in comparison to national d...

Computational analysis of swallowing mechanics underlying impaired epiglottic inversion.

The Laryngoscope
OBJECTIVES/HYPOTHESIS: Determine swallowing mechanics associated with the first and second epiglottic movements, that is, movement to horizontal and full inversion, respectively, to provide a clinical interpretation of impaired epiglottic function.

Classification of radiology reports for falls in an HIV study cohort.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: To identify patients in a human immunodeficiency virus (HIV) study cohort who have fallen by applying supervised machine learning methods to radiology reports of the cohort.

Development and Validation of an Algorithm to Identify Nonalcoholic Fatty Liver Disease in the Electronic Medical Record.

Digestive diseases and sciences
BACKGROUND AND AIMS: Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. Risk factors for NAFLD disease progression and liver-related outcomes remain incompletely understood due to the lack of computa...

Creation of a new longitudinal corpus of clinical narratives.

Journal of biomedical informatics
The 2014 i2b2/UTHealth Natural Language Processing (NLP) shared task featured a new longitudinal corpus of 1304 records representing 296 diabetic patients. The corpus contains three cohorts: patients who have a diagnosis of coronary artery disease (C...

A context-aware approach for progression tracking of medical concepts in electronic medical records.

Journal of biomedical informatics
Electronic medical records (EMRs) for diabetic patients contain information about heart disease risk factors such as high blood pressure, cholesterol levels, and smoking status. Discovering the described risk factors and tracking their progression ov...

Hidden Markov model using Dirichlet process for de-identification.

Journal of biomedical informatics
For the 2014 i2b2/UTHealth de-identification challenge, we introduced a new non-parametric Bayesian hidden Markov model using a Dirichlet process (HMM-DP). The model intends to reduce task-specific feature engineering and to generalize well to new da...

Comparison of UMLS terminologies to identify risk of heart disease using clinical notes.

Journal of biomedical informatics
The second track of the 2014 i2b2 challenge asked participants to automatically identify risk factors for heart disease among diabetic patients using natural language processing techniques for clinical notes. This paper describes a rule-based system ...