BACKGROUND: CST4 is associated with various cancers but its diagnostic value in colorectal cancer (CRC) has not been clearly established. This study aims to further validate the diagnostic value of CST4 in colorectal cancer using random forest models...
This study aimed to identify candidate diagnostic miRNAs from the serum of colorectal cancer (CRC) patients using Boruta, a wrapper-based feature selection technique, in combination with decision tree-based machine learning methods. We analyzed three...
BACKGROUNDS: Consensus molecular subtype 4 (CMS4) of colorectal cancer (CRC) is characterized by TGF-β activation, and generally accompanied with metastasis and recurrence. Nevertheless, molecular biomarkers and regulatory mechanisms underlying CMS4 ...
Colorectal cancer (CRC) remains a leading cause of cancer morbidity and mortality worldwide, yet improvements in survival have been modest despite advances in conventional therapies. The gut microbiota has emerged as a critical player in CRC pathogen...
Robotic surgery has now been widely applied in the treatment of colorectal cancer (CRC), driving significant growth in related research activities. This study aims to reveal the research hotspots, emerging frontiers, and future research trends in the...
This study aims to refine molecular subtypes via multi-omics data, develop a prognostic signature, and identify novel biomarkers in colorectal cancer (CRC). On the basis of the multi-omics data, the MOVICS R package was used to divide patients with C...
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Sep 26, 2025
PURPOSE: This study aimed to analyze the influencing factors of moderate-to-severe cancer-related fatigue (CRF) in colorectal cancer (CRC) chemotherapy patients and to develop a predictive risk stratification model.
BACKGROUND: Colorectal cancer (CRC) is the third most common cancer worldwide and poses a heavy burden on health care systems. Early screening for CRC through colonoscopy can effectively reduce both the incidence and mortality associated with CRC. Ho...
Colonoscopy is the gold standard for the examination and detection of polyps, with over 90% of polyps potentially progressing into colorectal cancer. Accurate polyp segmentation plays a pivotal role in the early diagnosis and treatment of colorectal ...
Tissue phenotypes, such as metabolic states, inflammation, and tumor properties, emerge from both molecular states and spatial cell organization. Spatial molecular assays provide an unbiased view of tissue architecture, enabling phenotype prediction....
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