AIMC Topic: Computational Biology

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Automated Diagnosis of Chest X-Ray for Early Detection of COVID-19 Disease.

Computational and mathematical methods in medicine
In March 2020, the World Health Organization announced the COVID-19 pandemic, its dangers, and its rapid spread throughout the world. In March 2021, the second wave of the pandemic began with a new strain of COVID-19, which was more dangerous for som...

A Deep Learning-Based Classification Method for Different Frequency EEG Data.

Computational and mathematical methods in medicine
In recent years, the research on electroencephalography (EEG) has focused on the feature extraction of EEG signals. The development of convenient and simple EEG acquisition devices has produced a variety of EEG signal sources and the diversity of the...

TopProperty: Robust Metaprediction of Transmembrane and Globular Protein Features Using Deep Neural Networks.

Journal of chemical theory and computation
Transmembrane proteins (TMPs) are critical components of cellular life. However, due to experimental challenges, the number of experimentally resolved TMP structures is severely underrepresented in databases compared to their cellular abundance. Pred...

A Wavelet-Based Learning Model Enhances Molecular Prognosis in Pancreatic Adenocarcinoma.

BioMed research international
Genome-wide omics technology boosts deep interrogation into the clinical prognosis and inherent mechanism of pancreatic oncology. Classic LASSO methods coequally treat all candidates, ignoring individual characteristics, thus frequently deteriorating...

A Deep Learning Approach for Predicting Antigenic Variation of Influenza A H3N2.

Computational and mathematical methods in medicine
Modeling antigenic variation in influenza (flu) virus A H3N2 using amino acid sequences is a promising approach for improving the prediction accuracy of immune efficacy of vaccines and increasing the efficiency of vaccine screening. Antigenic drift a...

Comparing the Prognostic Value of Stress Myocardial Perfusion Imaging by Conventional and Cadmium-Zinc Telluride Single-Photon Emission Computed Tomography through a Machine Learning Approach.

Computational and mathematical methods in medicine
We compared the prognostic value of myocardial perfusion imaging (MPI) by conventional- (C-) single-photon emission computed tomography (SPECT) and cadmium-zinc-telluride- (CZT-) SPECT in a cohort of patients with suspected or known coronary artery d...

Identification of efflux proteins based on contextual representations with deep bidirectional transformer encoders.

Analytical biochemistry
Efflux proteins are the transport proteins expressed in the plasma membrane, which are involved in the movement of unwanted toxic substances through specific efflux pumps. Several studies based on computational approaches have been proposed to predic...

Spatial Prediction of COVID-19 in China Based on Machine Learning Algorithms and Geographically Weighted Regression.

Computational and mathematical methods in medicine
COVID-19 has swept through the world since December 2019 and caused a large number of patients and deaths. Spatial prediction on the spread of the epidemic is greatly important for disease control and management. In this study, we predicted the cumul...

Sentiment Analysis Based on the Nursing Notes on In-Hospital 28-Day Mortality of Sepsis Patients Utilizing the MIMIC-III Database.

Computational and mathematical methods in medicine
In medical visualization, nursing notes contain rich information about a patient's pathological condition. However, they are not widely used in the prediction of clinical outcomes. With advances in the processing of natural language, information begi...

The information theory of developmental pruning: Optimizing global network architectures using local synaptic rules.

PLoS computational biology
During development, biological neural networks produce more synapses and neurons than needed. Many of these synapses and neurons are later removed in a process known as neural pruning. Why networks should initially be over-populated, and the processe...