AIMC Topic: Computational Biology
Clear Filters Showing 191 to 200 of 4246 articles
Molecular structure and mechanism of protein MSMB, TPPP3, SPI1: Construction of novel 4 pancreatic cancer-related protein signatures model based on machine learning.
International journal of biological macromolecules
Mar 12, 2025
The high mortality rate of pancreatic cancer is closely related to its inconspicuous early symptoms and difficult diagnosis. In recent years, with the rapid development of proteomics and bioinformatics, the use of machine learning technology to analy...
scMDCL: A Deep Collaborative Contrastive Learning Framework for Matched Single-Cell Multiomics Data Clustering.
Journal of chemical information and modeling
Mar 11, 2025
Single-cell multiomics clustering integrates multiple omics data to analyze cellular heterogeneity and is crucial for uncovering complex biological processes and disease mechanisms. However, existing matched single-cell multiomics clustering methods ...
RBPsuite 2.0: an updated RNA-protein binding site prediction suite with high coverage on species and proteins based on deep learning.
BMC biology
Mar 11, 2025
BACKGROUND: RNA-binding proteins (RBPs) play crucial roles in many biological processes, and computationally identifying RNA-RBP interactions provides insights into the biological mechanism of diseases associated with RBPs.
Predicting the diversity of photosynthetic light-harvesting using thermodynamics and machine learning.
PLoS computational biology
Mar 11, 2025
Oxygenic photosynthesis is responsible for nearly all biomass production on Earth, and may have been a prerequisite for establishing a complex biosphere rich in multicellular life. Life on Earth has evolved to perform photosynthesis in a wide range o...
Biochemical Characterization of Disease-Associated Variants of Human Ornithine Transcarbamylase.
ACS chemical biology
Mar 10, 2025
Human ornithine transcarbamylase deficiency (OTCD) is the most common ureagenesis disorder in the world. OTCD is an X-linked genetic deficiency in which patients experience hyperammonemia to varying degrees depending on the severity of the genetic mu...
Cancer Drug Sensitivity Prediction Based on Deep Transfer Learning.
International journal of molecular sciences
Mar 10, 2025
In recent years, many approved drugs have been discovered using phenotypic screening, which elaborates the exact mechanisms of action or molecular targets of drugs. Drug susceptibility prediction is an important type of phenotypic screening. Large-sc...
Elucidating the role of KCTD10 in coronary atherosclerosis: Harnessing bioinformatics and machine learning to advance understanding.
Scientific reports
Mar 10, 2025
Atherosclerosis (AS) is increasingly recognized as a chronic inflammatory disease that significantly compromises vascular health and serves as a major contributor to cardiovascular diseases. KCTD10, a protein implicated in a variety of biological pro...
Comprehensive integration of diagnostic biomarker analysis and immune cell infiltration features in sepsis via machine learning and bioinformatics techniques.
Frontiers in immunology
Mar 10, 2025
INTRODUCTION: Sepsis, a critical medical condition resulting from an irregular immune response to infection, leads to life-threatening organ dysfunction. Despite medical advancements, the critical need for research into dependable diagnostic markers ...
BacTermFinder: a comprehensive and general bacterial terminator finder using a CNN ensemble.
NAR genomics and bioinformatics
Mar 8, 2025
A terminator is a DNA region that ends the transcription process. Currently, multiple computational tools are available for predicting bacterial terminators. However, these methods are specialized for certain bacteria or terminator type (i.e. intrins...
DeepMVD: A Novel Multiview Dynamic Feature Fusion Model for Accurate Protein Function Prediction.
Journal of chemical information and modeling
Mar 7, 2025
Proteins, as the fundamental macromolecules of life, play critical roles in various biological processes. Recent advancements in intelligent protein function prediction methods leverage sequences, structures, and biomedical literature data. Among the...
Stay Ahead of Medical AI
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 31144
- Neural Networks, Computer 29771
- Algorithms 26915
- Deep Learning 26421
- Artificial Intelligence 24361
- Robotics 13323
- Image Processing, Computer-Assisted 9552
- Retrospective Studies 9137
- Magnetic Resonance Imaging 6200
- Reproducibility of Results 5602
- Tomography, X-Ray Computed 4778
- Support Vector Machine 4696
- Computational Biology 4246
- Brain 4056
- Computer Simulation 3887
Recent Journals
- Scientific reports 6082
- Sensors (Basel, Switzerland) 4794
- PloS one 4051
- Neural networks : the official journal of the International Neural Network Society 2930
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1868
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1278
- IEEE journal of biomedical and health informatics 1137
- Journal of chemical information and modeling 1006
- Nature communications 959
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 862
- Briefings in bioinformatics 853
- IEEE transactions on neural networks and learning systems 830