AIMC Topic: Cornea
Clear Filters Showing 61 to 70 of 94 articles
Automatic diagnosis of fungal keratitis using data augmentation and image fusion with deep convolutional neural network.
Computer methods and programs in biomedicine
Aug 9, 2019
BACKGROUND AND OBJECTIVES: Fungal keratitis is caused by inflammation of the cornea that results from infection by fungal organisms. The lack of an early effective diagnosis often results in serious complications even blindness. Confocal microscopy i...
KeratoDetect: Keratoconus Detection Algorithm Using Convolutional Neural Networks.
Computational intelligence and neuroscience
Jan 23, 2019
Keratoconus (KTC) is a noninflammatory disorder characterized by progressive thinning, corneal deformation, and scarring of the cornea. The pathological mechanisms of this condition have been investigated for a long time. In recent years, this diseas...
Keratoconus severity identification using unsupervised machine learning.
PloS one
Nov 6, 2018
We developed an unsupervised machine learning algorithm and applied it to big corneal parameters to identify and monitor keratoconus stages. A big dataset of corneal swept source optical coherence tomography (OCT) images of 12,242 eyes acquired from ...
Enhanced Tomographic Assessment to Detect Corneal Ectasia Based on Artificial Intelligence.
American journal of ophthalmology
Aug 9, 2018
PURPOSE: To improve the detection of corneal ectasia susceptibility using tomographic data.
Corneal Topography
Diagnostic Techniques, Ophthalmological
Keratomileusis, Laser In Situ
Slit Lamp Microscopy
Tomography
Corneal Pachymetry
Humans
Artificial Intelligence
Case-Control Studies
Retrospective Studies
Sensitivity and Specificity
ROC Curve
Dilatation, Pathologic
Keratoconus
Female
Cornea
Adult
Male
Middle Aged
Ocular Distribution and Pharmacokinetics of Lifitegrast in Pigmented Rabbits and Mass Balance in Beagle Dogs.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Dec 21, 2017
PURPOSE: Lifitegrast is approved in the United States for the treatment of dry eye disease (DED). We assessed lifitegrast's ocular distribution/pharmacokinetic profile in rabbits, and C-lifitegrast mass balance/excretion in dogs.
Corneal power evaluation after myopic corneal refractive surgery using artificial neural networks.
Biomedical engineering online
Nov 15, 2016
BACKGROUND: Efficacy and high availability of surgery techniques for refractive defect correction increase the number of patients who undergo to this type of surgery. Regardless of that, with increasing age, more and more patients must undergo catara...
Molecular mechanisms of suberoylanilide hydroxamic acid in the inhibition of TGF-β1-mediated canine corneal fibrosis.
Veterinary ophthalmology
Nov 12, 2015
OBJECTIVE: To investigate molecular mechanisms mediating anti-fibrotic effect of SAHA in the canine cornea using an in vitro model. We hypothesized that SAHA attenuates corneal fibrosis by modulating Smad-dependent and, to a lesser extent, Smad-indep...
Artificial Intelligence Aided Analysis of Anterior Segment Optical Coherence Tomography Imaging to Monitor the Device-Cornea Joint After Synthetic Cornea Implantation.
Translational vision science & technology
Jun 2, 2025
PURPOSE: The purpose of this study was to assess the utility of artificial intelligence (AI) assisted analysis of anterior segment optical coherence tomography (AS-OCT) imaging of the device-cornea joint in predicting outcomes of an intrastromal synt...
Reconstruction of highly and extremely aberrated wavefront for ocular Shack-Hartmann sensor using multi-task Attention-UNet.
Experimental eye research
Jun 1, 2025
In certain ocular conditions, such as in eyes with keratoconus or after corneal laser surgery, Higher Order Aberrations (HOAs) may be dramatically elevated. Accurately recording interpretable wavefronts in such highly aberrated eyes using Shack-Hartm...
MCOA: A Comprehensive Multimodal Dataset for Advancing Deep Learning in Corneal Opacity Assessment.
Scientific data
May 30, 2025
Corneal opacity remains a major global cause of vision impairment. Its severity is typically assessed subjectively by clinicians using slit lamp examinations of the anterior segment. While anterior segment optical coherence tomography (AS-OCT) provid...
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