In this research work, machine learning techniques are used to classify magnetic resonance imaging brain scans of people with Alzheimer's disease. This work deals with binary classification between Alzheimer's disease and cognitively normal. Supervis...
Studies in health technology and informatics
Jan 1, 2019
We study the way dynamics affects modelling in chronic heart failure (CHF) tasks. By dynamics we understand the patient history and the appearance of new events, states and variables changing in time. The goal is to understand what impact past data h...
Journal of X-ray science and technology
Jan 1, 2019
BACKGROUND: Hip fracture is considered one of the salient disability factors across the global population. People with hip fractures are prone to become permanently disabled or die from complications. Although currently the premier determiner, bone m...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2019
Inference of gene regulatory networks (GRNs) from time series data is a well-established field in computational systems biology. Most approaches can be broadly divided in two families: model-based and model-free methods. These two families are highly...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2019
In this chapter, we introduce the reader to a popular family of machine learning algorithms, called decision trees. We then review several approaches based on decision trees that have been developed for the inference of gene regulatory networks (GRNs...
INTRODUCTION: The development of a novel drug is an extremely complicated process that includes the target identification, design and manufacture, and proper therapy of the novel drug, as well as drug dose selection, drug efficacy evaluation, and adv...
Clinical orthopaedics and related research
Oct 1, 2018
BACKGROUND: Several studies have identified prognostic factors for patients with chondrosarcoma, but there are few studies investigating the accuracy of computationally intensive methods such as machine learning. Machine learning is a type of artific...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2018
This paper presents a novel framework to detect the status of intraocular pressure (normal/high) using solely frontal eye image analysis. The framework is based on machine learning approaches to extract six features from frontal eye images. These fea...
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Apr 1, 2018
Sleep stage classification constitutes an important preliminary exam in the diagnosis of sleep disorders. It is traditionally performed by a sleep expert who assigns to each 30 s of the signal of a sleep stage, based on the visual inspection of signa...
Journal of X-ray science and technology
Jan 1, 2018
BACKGROUND: Accurate measurement of bone mineral density (BMD) in dual-energy X-ray absorptiometry (DXA) is essential for proper diagnosis of osteoporosis. Calculation of BMD requires precise bone segmentation and subtraction of soft tissue absorptio...
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