Automatic segmentation of the hippocampus from 3D magnetic resonance imaging mostly relied on multi-atlas registration methods. In this work, we exploit recent advances in deep learning to design and implement a fully automatic segmentation method, o...
Our objective is to evaluate the effectiveness of efficient convolutional neural networks (CNNs) for abnormality detection in chest radiographs and investigate the generalizability of our models on data from independent sources. We used the National ...
MOTIVATION: Computationally predicting disease genes helps scientists optimize the in-depth experimental validation and accelerates the identification of real disease-associated genes. Modern high-throughput technologies have generated a vast amount ...
We address the problem of prostate lesion detection, localization, and segmentation in T2W magnetic resonance (MR) images. We train a deep convolutional encoder-decoder architecture to simultaneously segment the prostate, its anatomical structure, an...
Positron emission tomography (PET) imaging is an effective tool used in determining disease stage and lesion malignancy; however, radiation exposure to patients and technicians during PET scans continues to draw concern. One way to minimize radiation...
We hypothesize that convolutional neural networks (CNN) can be used to predict neoadjuvant chemotherapy (NAC) response using a breast MRI tumor dataset prior to initiation of chemotherapy. An institutional review board-approved retrospective review o...
Mathematical biosciences and engineering : MBE
Sep 30, 2019
Copy number variations (CNVs) play an important role in many types of cancer. With the rapid development of next generation sequencing (NGS) techniques, many methods for detecting CNVs of a single sample have emerged: (i) require genome-wide data of ...
Automatic and accurate segmentation of intravascular optical coherence tomography imagery is of great importance in computer-aided diagnosis and in treatment of cardiovascular diseases. However, this task has not been well addressed for two reasons. ...
The identification of interactions between drugs/compounds and their targets is crucial for the development of new drugs. In vitro screening experiments (i.e. bioassays) are frequently used for this purpose; however, experimental approaches are insuf...
Mathematical biosciences and engineering : MBE
Sep 26, 2019
Public water supply facilities are vulnerable to intentional intrusion. In particular, Water Distribution Network (WDN) has become one of the most important public facilities that are prone to be attacked because of its wide coverage and constant ope...
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